Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | VNN1 | O95497 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 2/20 | 0.43 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.43 |
| ▸ | BCR | P11274 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5128240 | 0.84 | RXFP1 (0.56) | RXFP1SMN1; SMN2NPC1MAPTADORA3 | |
| SCHEMBL1549873 | 0.83 | RXFP1 (0.67) | RXFP1TP53SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9607405 | 0.83 | RXFP1 (0.71) | RXFP1TP53SMN1; SMN2NPC1RAB9A | |
| SCHEMBL5129590 | 0.83 | LDHA (0.59) | RXFP1TP53SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1758365 | 0.82 | ABL1 (0.57) | RXFP1NPC1RAB9AMAPTADORA3 | |
| SCHEMBL12647411 | 0.82 | HDAC3 (0.49) | RXFP1SMN1; SMN2MAPTHDAC3HDAC1 | |
| SCHEMBL9607063 | 0.82 | LMNA (0.53) | MAPTVNN1HDAC3HDAC1HDAC2 | |
| SCHEMBL6141283 | 0.81 | HDAC3 (0.54) | TP53SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL9607429 | 0.78 | TRPV3 (0.46) | RXFP1TP53SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2056330 | 0.77 | SMN1; SMN2 (0.54) | TP53SMN1; SMN2NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |