Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | PTGFR | P43088 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 8/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8515625 | 0.91 | ACP1 (0.45) | ACP1PTGFRSCN10ACHRM5SCN2A | |
| SCHEMBL8515384 | 0.86 | ACP1 (0.44) | ACP1PTGFRSCN10ASCN2A | |
| SCHEMBL8514758 | 0.75 | DHODH (0.44) | ACP1PTGFRSCN10A | |
| SCHEMBL8511573 | 0.73 | KDM4E (0.42) | ACP1CTNNB1SCN10ASCN2APPARD | |
| SCHEMBL13049103 | 0.70 | SCN10A (0.37) | ARSCN10ACHRM5SCN2A | |
| SCHEMBL28253958 | 0.69 | PDE10A (0.48) | ACP1TRPM8SCN10ASCN2A | |
| SCHEMBL22314946 | 0.69 | DGAT1 (0.50) | ACP1SCN10ACHRM5 | |
| SCHEMBL8514255 | 0.69 | PDE10A (0.44) | ACP1PTGFRCTNNB1TCF7L2TRPM8 | |
| SCHEMBL8514251 | 0.69 | PDE10A (0.44) | ACP1PTGFRCTNNB1TCF7L2TRPM8 | |
| SCHEMBL8515893 | 0.68 | CYP3A4 (0.44) | PTGFRTRPM8SCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |