Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.49 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.42 |
| ▸ | ABL1 | P00519 | 4/20 | 0.41 |
| ▸ | FAAH | O00519 | 3/20 | 0.40 |
| ▸ | CTSA | P10619 | 1/20 | 0.40 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9607151 | 0.79 | FAAH (0.45) | SCN10ASCN9AFAAHKCNH2PDE2A | |
| SCHEMBL4542016 | 0.78 | PDE2A (0.54) | PDE2A | |
| SCHEMBL9606759 | 0.74 | SCN10A (0.61) | PRMT6SCN10ACYP11B1CYP11B2SCN9A | |
| SCHEMBL4592299 | 0.73 | PRMT6 (0.61) | PRMT6SCN10ACYP11B1CYP11B2ABL1 | |
| SCHEMBL641681 | 0.73 | SCN10A (0.63) | PRMT6SCN10ACYP11B1CYP11B2ABL1 | |
| SCHEMBL3747476 | 0.72 | CYP11B2 (0.49) | PRMT6SCN10ACYP11B2SCN9AABL1 | |
| SCHEMBL12720203 | 0.72 | SCN10A (0.58) | PRMT6SCN10ACYP11B1CYP11B2SCN9A | |
| SCHEMBL30357895 | 0.72 | PDE2A (0.44) | SCN9AFAAHPDE2A | |
| SCHEMBL9607167 | 0.72 | PDE2A (0.48) | PDE2A | |
| SCHEMBL1230338 | 0.71 | CYP11B1 (0.53) | PRMT6SCN10ACYP11B1CYP11B2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |