Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8531036 | 0.93 | CYP2C9 (0.44) | MAT2APDE10ACYP2C9PTGS2DDR1 | |
| SCHEMBL8532926 | 0.93 | MAT2A (0.51) | MAT2A | |
| SCHEMBL8537794 | 0.89 | MAT2A (0.50) | MAT2ACYP2C9 | |
| SCHEMBL9607503 | 0.86 | MAT2A (0.47) | MAT2ACYP2C9 | |
| SCHEMBL8535303 | 0.83 | MAT2A (0.55) | MAT2ACNR1 | |
| SCHEMBL9607504 | 0.82 | MAT2A (0.46) | MAT2ACYP2C9 | |
| SCHEMBL20983234 | 0.80 | MAT2A (0.58) | MAT2A | |
| SCHEMBL8536502 | 0.80 | MAT2A (0.43) | MAT2ACNR1DDR1 | |
| SCHEMBL8532964 | 0.80 | MAT2A (0.52) | MAT2APDE10A | |
| SCHEMBL8538786 | 0.78 | MAT2A (0.45) | MAT2ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |