Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | RHEB | Q15382 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8535303 | 0.88 | MAT2A (0.55) | MAT2ACYP3A4TP53SMN1; SMN2CNR1 | |
| SCHEMBL8532926 | 0.86 | MAT2A (0.51) | MAT2ASLC2A1CYP3A4 | |
| SCHEMBL8533461 | 0.79 | MAT2A (0.56) | MAT2ASLC2A1KIF11 | |
| SCHEMBL9607503 | 0.79 | MAT2A (0.47) | MAT2A | |
| SCHEMBL8537070 | 0.79 | MAT2A (0.57) | MAT2ASLC2A1CYP3A4TP53SMN1; SMN2 | |
| SCHEMBL8532528 | 0.78 | MAT2A (0.48) | MAT2ACNR1PTGESGRM2KIF11 | |
| SCHEMBL8535293 | 0.78 | MAT2A (0.48) | MAT2ACNR1PTGESGRM2KIF11 | |
| SCHEMBL9607468 | 0.78 | MAT2A (0.44) | MAT2ACNR1 | |
| SCHEMBL8538462 | 0.78 | MAT2A (0.52) | MAT2ACNR1KIF11 | |
| SCHEMBL8514142 | 0.77 | ALOX5 (0.48) | PTGESALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | claimed |
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |