SCHEMBL9607523

SCHEMBL9607523

CCOC(=O)Oc1ccc(C(=CC=C(c2ccc(C)cc2)c2ccc(C)cc2)c2ccc(OC(=O)OCC)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.44
KMT2A Q03164 7/20 0.44
MAOB P27338 2/20 0.43
MEN1 O00255 1/20 0.43
USP2 O75604 1/20 0.41
MMP2 P08253 1/20 0.41
MMP9 P14780 1/20 0.41
MMP8 P22894 1/20 0.41
MMP14 P50281 1/20 0.41
PPARG P37231 1/20 0.41
PPARD Q03181 1/20 0.41
PPARA Q07869 1/20 0.41
PRSS1 P07477 2/20 0.39
ACR P10323 2/20 0.39
GAA P10253 2/20 0.39
ESR1 P03372 1/20 0.39
RECQL P46063 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HIF1A Q16665 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13950824 0.88 MAOB (0.44) LMNAKMT2AMAOBMEN1MMP2
SCHEMBL1598705 0.87 LMNA (0.57) LMNAKMT2AMEN1USP2MMP2
SCHEMBL279048 0.84 MAPT (0.40) LMNAKMT2AMEN1USP2MMP2
SCHEMBL6451238 0.81 ALDH1A1 (0.55) LMNAKMT2AMEN1MMP2MMP9
SCHEMBL8983109 0.79 KMT2A (0.46) LMNAKMT2AMEN1MMP2MMP9
Urethane SCHEMBL21771806 0.79 ALOX15 (0.52) LMNAKMT2AMEN1USP2MMP2
SCHEMBL3789020 0.78 HSD17B10 (0.53) KMT2AUSP2MMP2MMP9MMP8
SCHEMBL23802411 0.77 KMT2A (0.53) KMT2AMEN1MMP2MMP9MMP8
SCHEMBL929726 0.77 KMT2A (0.45) LMNAKMT2AMEN1MMP2MMP9
SCHEMBL21771930 0.76 KMT2A (0.42) LMNAKMT2AMAOBMEN1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8273517-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-09-25 US disclosed
US-20120134713-A1 METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2012-05-31 US disclosed