SCHEMBL1598705

SCHEMBL1598705

CCOC(=O)Oc1ccc(C)cc1

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.57
KMT2A Q03164 8/20 0.49
MMP2 P08253 1/20 0.49
MMP9 P14780 1/20 0.49
MMP8 P22894 1/20 0.49
MMP14 P50281 1/20 0.49
MEN1 O00255 5/20 0.49
ALDH1A1 P00352 2/20 0.48
GAA P10253 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.46
POLB P06746 1/20 0.46
SOAT1 P35610 1/20 0.44
KDM4E B2RXH2 1/20 0.44
MAPT P10636 1/20 0.44
CA2 P00918 1/20 0.43
HTT P42858 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
USP2 O75604 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6451238 0.94 ALDH1A1 (0.55) LMNAKMT2AMMP2MMP9MMP8
Urethane SCHEMBL21771806 0.91 ALOX15 (0.52) LMNAKMT2AMMP2MMP9MMP8
SCHEMBL9607523 0.87 LMNA (0.44) LMNAKMT2AMMP2MMP9MMP8
SCHEMBL1598665 0.86 LMNA (0.52) LMNAKMT2AMMP2MMP9MMP14
SCHEMBL8536318 0.86 CA2 (0.55) LMNAKMT2AMMP2MMP9MMP8
SCHEMBL6894576 0.86 GAA (0.51) LMNAKMT2AMMP2MMP9MMP8
SCHEMBL15899401 0.86 LMNA (0.47) LMNAKMT2AMMP2MMP9MMP8
SCHEMBL727948 0.85 ELANE (0.52) LMNAKMT2AMEN1ALDH1A1L3MBTL1
SCHEMBL16732335 0.84 LMNA (0.46) LMNAKMT2AMMP2MMP9MMP8
SCHEMBL47792 0.84 LMNA (0.70) LMNAKMT2AMEN1ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250212873-A1 VOLATILE HDAC INHIBITORS FOR THERAPEUTIC AND PLANT APPLICATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-07-03 US claimed
EP-4482306-A1 VOLATILE HDAC INHIBITORS FOR THERAPEUTIC AND PLANT APPLICATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-01-01 EP claimed
WO-2023192424-A1 VOLATILE HD AC INHIBITORS FOR THERAPEUTIC AND PLANT APPLICATIONS CROSS-REFERENCE TO RELATED APPLICATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-10-05 WO claimed
US-20250212873-A1 VOLATILE HDAC INHIBITORS FOR THERAPEUTIC AND PLANT APPLICATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-07-03 US disclosed
EP-4482306-A1 VOLATILE HDAC INHIBITORS FOR THERAPEUTIC AND PLANT APPLICATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-01-01 EP disclosed
EP-4446310-A1 METHOD FOR PRODUCING BLOCKED ISOCYANATE COMPOUND AND METHOD FOR PRODUCING ISOCYANATE COMPOUND Asahi Kasei Kabushiki Kaisha (JP) 2024-10-16 EP disclosed
CN-115677999-B Polycarbonate and preparation method and application thereof 华为技术有限公司 2024-05-14 CN disclosed
WO-2023192424-A1 VOLATILE HD AC INHIBITORS FOR THERAPEUTIC AND PLANT APPLICATIONS CROSS-REFERENCE TO RELATED APPLICATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-10-05 WO disclosed
CN-115677999-A Polycarbonate and preparation method and application thereof 华为技术有限公司 2023-02-03 CN disclosed
EP-3838892-B1 METHOD FOR PRODUCING ISOCYANATE ASAHI CHEMICAL IND (JP) 2022-10-12 EP disclosed
US-11318111-B2 CCL5 inhibitors LAPKO INC (US) 2022-05-03 US disclosed
EP-0760359-A1 Method for preparing aromatic carbonate MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1997-03-05 EP disclosed
US-5463102-A Process for the continuous production of aryl carbonates BAYER AKTIENGESELLSCHAFT (DE) 1995-10-31 US disclosed
CN-1030073-C Process for continuous production of aryl carbonate ASAHI CHEMICAL IND (JP) 1995-10-18 CN disclosed
EP-0608710-A1 Process for the continuous preparation of aryle carbonates BAYER AG (DE) 1994-08-03 EP disclosed
EP-0461274-B1 PROCESS FOR CONTINUOUSLY PRODUCING AROMATIC CARBONATE ASAHI CHEMICAL IND (JP) 1994-06-15 EP disclosed
US-5210268-A Ester interchange, catalysis ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1993-05-11 US disclosed
CN-1064677-A PROCESS FOR PREPARING AROMATIC CARBONATE ASAHI CHEMICAL IND (JP) 1992-09-23 CN disclosed
EP-0461274-A1 PROCESS FOR CONTINUOUSLY PRODUCING AROMATIC CARBONATE Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1991-12-18 EP disclosed
US-4447365-A ORGANOLEPTIC AGENT INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1984-05-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11318111-B2 CCL5 inhibitors CCL5, CCL11, CCR5 LMNA 4533/4885KMT2A 4842/4885MMP2 885/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.