Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 4/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.44 |
| ▸ | PDK3 | Q15120 | 4/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10046434 | 0.87 | SMN1; SMN2 (0.58) | SMN1; SMN2HTTMEN1KMT2AMAPK1 | |
| SCHEMBL3438880 | 0.79 | HTT (0.50) | SMN1; SMN2HTTMEN1KMT2AMAPK1 | |
| SCHEMBL3612815 | 0.78 | MEN1 (0.67) | SMN1; SMN2MEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL30623497 | 0.78 | MEN1 (0.67) | SMN1; SMN2MEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL29524654 | 0.77 | HPGD (0.66) | HTTMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL646296 | 0.77 | HPGD (0.66) | HTTMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL476919 | 0.77 | LMNA (0.69) | SMN1; SMN2MAPK1ALDH1A1HPGDLMNA | |
| SCHEMBL13043443 | 0.77 | ALDH1A1 (0.50) | SMN1; SMN2MEN1KMT2AMAPK1PKM | |
| Hydrochloric Acid SCHEMBL28564415 | 0.77 | MEN1 (0.65) | SMN1; SMN2MEN1KMT2AMAPK1PKM | |
| SCHEMBL3785379 | 0.77 | ALDH1A1 (0.50) | SMN1; SMN2MEN1KMT2AMAPK1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120135975-A1 | Substituted Esters as Cannabinoid-1 Receptor Modulators | MERCK & CO., INC. (US) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135975-A1 | Substituted Esters as Cannabinoid-1 Receptor Modulators | CNR1, CNR2, FAAH | SMN1; SMN2 398/4885HTT 2006/4885MEN1 248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.