Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10046434 | 0.91 | SMN1; SMN2 (0.58) | HTTSMN1; SMN2ALDH1A1HPGDMAOA | |
| SCHEMBL9607572 | 0.79 | SMN1; SMN2 (0.50) | HTTSMN1; SMN2ALDH1A1HPGDPOLB | |
| SCHEMBL3438878 | 0.74 | CETP (0.58) | ALDH1A1POLBKDM4EMEN1KMT2A | |
| SCHEMBL10046431 | 0.71 | MAPT (0.49) | HTTSMN1; SMN2ALDH1A1HPGDPOLB | |
| SCHEMBL10046433 | 0.71 | MDM4 (0.58) | HTTSMN1; SMN2ALDH1A1HPGDPOLB | |
| SCHEMBL10564460 | 0.71 | ALDH1A1 (0.57) | HTTSMN1; SMN2ALDH1A1HPGDMAOA | |
| SCHEMBL3438876 | 0.71 | HPGD (0.43) | HTTSMN1; SMN2ALDH1A1HPGDPOLB | |
| SCHEMBL3438879 | 0.71 | CETP (0.50) | SMN1; SMN2ALDH1A1POLBGAAHSD17B10 | |
| SCHEMBL12163530 | 0.71 | GAA (0.54) | SMN1; SMN2ALDH1A1HPGDPOLBCYP2C19 | |
| SCHEMBL631133 | 0.71 | ALDH1A1 (0.57) | HTTSMN1; SMN2ALDH1A1HPGDMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120101271-A1 | DIAMINE SYNTHESIS VIA CATALYTIC C-H AMINATION OF AZIDES | NATIONAL SCIENCE FOUNDATION | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101271-A1 | DIAMINE SYNTHESIS VIA CATALYTIC C-H AMINATION OF AZIDES | DOHH, AOC1, ESD | HTT 1318/4885SMN1; SMN2 1784/4885ALDH1A1 233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.