Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 2/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL212899 | 0.92 | MAPK1 (0.34) | MAPK1ANO1ABL1PTGES | |
| SCHEMBL213122 | 0.86 | ANO1 (0.34) | TGFBR1MAPK1ANO1PTGES | |
| SCHEMBL2726612 | 0.84 | ANO1 (0.35) | TGFBR1MAPK1ANO1ABL1PDCD1 | |
| SCHEMBL212510 | 0.84 | TGFBR1 (0.32) | TGFBR1MAPK1ANO1ABL1 | |
| SCHEMBL212408 | 0.84 | ANO1 (0.34) | MAPK1ANO1ABL1PTGES | |
| SCHEMBL2722512 | 0.82 | ABL1 (0.36) | ANO1ABL1 | |
| SCHEMBL211930 | 0.81 | ABL1 (0.34) | MAPK1ANO1ABL1 | |
| SCHEMBL8511079 | 0.81 | MAPK1 (0.37) | MAPK1ANO1ABL1 | |
| SCHEMBL2724403 | 0.81 | GSK3B (0.36) | ANO1ABL1PTGES | |
| SCHEMBL2725708 | 0.81 | ABL1 (0.32) | MAPK1ANO1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120135964-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | QIAN XIANGPING (US) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135964-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | MYLK, MYH2, MYH10 | TGFBR1 2802/4885MAPK1 2926/4885ANO1 1073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.