Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | TP53 | P04637 | 4/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL214098 | 0.90 | MAPT (0.38) | MAPTSMN1; SMN2TP53EPHX2KDM4E | |
| SCHEMBL211761 | 0.89 | MAPT (0.36) | MAPTSMN1; SMN2TP53EPHX2KDM4E | |
| SCHEMBL211762 | 0.89 | MAPT (0.36) | MAPTSMN1; SMN2TP53EPHX2KDM4E | |
| SCHEMBL211760 | 0.89 | MAPT (0.36) | MAPTSMN1; SMN2TP53EPHX2KDM4E | |
| SCHEMBL213927 | 0.89 | MAPT (0.36) | MAPTSMN1; SMN2TP53EPHX2KDM4E | |
| SCHEMBL2728354 | 0.88 | MAPT (0.36) | MAPTSMN1; SMN2TP53EPHX2KDM4E | |
| SCHEMBL210856 | 0.87 | MAPT (0.35) | MAPTSMN1; SMN2TP53EPHX2KDM4E | |
| SCHEMBL2727292 | 0.87 | MAPT (0.35) | MAPTSMN1; SMN2TP53EPHX2KDM4E | |
| SCHEMBL211389 | 0.87 | MAPT (0.35) | MAPTSMN1; SMN2TP53EPHX2KDM4E | |
| SCHEMBL211390 | 0.87 | MAPT (0.35) | MAPTSMN1; SMN2TP53EPHX2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120135964-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | QIAN XIANGPING (US) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135964-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | MYLK, MYH2, MYH10 | MAPT 530/4885SMN1; SMN2 252/4885TP53 2206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.