Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9607976 | 0.84 | MAPT (0.38) | RAB9AHTTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8497061 | 0.82 | RAB9A (0.64) | RAB9AHTTSMN1; SMN2LMNARXFP1 | |
| SCHEMBL9607973 | 0.82 | KMT2A (0.53) | RAB9AHTTSMN1; SMN2LMNAMEN1 | |
| SCHEMBL9608188 | 0.79 | AURKA (0.42) | RAB9AHTTRXFP1KDM4EALDH1A1 | |
| SCHEMBL9608214 | 0.79 | KMT2A (0.35) | RAB9ASMN1; SMN2LMNARXFP1GAA | |
| SCHEMBL9608215 | 0.79 | KMT2A (0.36) | RAB9ASMN1; SMN2LMNARXFP1POLB | |
| SCHEMBL9607975 | 0.78 | PDE4A (0.46) | MEN1KMT2ATNFNOD1 | |
| SCHEMBL10445850 | 0.78 | MEN1 (0.34) | RAB9ALMNAPOLBKDM4EALDH1A1 | |
| SCHEMBL8504062 | 0.77 | LDHA (0.57) | RAB9AHTTSMN1; SMN2LMNAPOLB | |
| SCHEMBL9608217 | 0.77 | KMT2A (0.35) | RAB9ASMN1; SMN2LMNARXFP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9089139-B2 | Agri-horticultural pest control compositions comprising 4-(3-butynyl)aminopyrimidine derivatives | SDS BIOTECH K. K. (JP) | 2015-07-28 | — | — | US | disclosed |
| US-9089139-B2 | Agri-horticultural pest control compositions comprising 4-(3-butynyl)aminopyrimidine derivatives | SDS BIOTECH K. K. (JP) | 2015-07-28 | — | — | US | disclosed |
| US-8586505-B2 | 4-(3-butynyl)aminopyrimidine derivatives as pest control agents for agricultural and horticultural use | SDS BIOTECH K. K. (JP) | 2013-11-19 | — | — | US | disclosed |
| US-20130296271-A1 | Agri-Horticultural Pest Control Compositions Comprising 4-(3-Butynyl)Aminopyrimidine Derivatives | SDS BIOTECH K.K. (JP) | 2013-11-07 | — | — | US | disclosed |
| US-20130296271-A1 | Agri-Horticultural Pest Control Compositions Comprising 4-(3-Butynyl)Aminopyrimidine Derivatives | SDS BIOTECH K.K. (JP) | 2013-11-07 | — | — | US | disclosed |
| US-20120136150-A1 | 4-(3-Butynyl)Aminopyrimidine Derivatives as Pest Control Agents for Agricultural and Horticultural Use | SDS BIOTECH K.K. (JP) | 2012-05-31 | — | — | US | disclosed |
| WO-2011007839-A1 | 4-(3-BUTYNYL)AMINOPYRIMIDINE DERIVATIVES AS PEST CONTROL AGENTS FOR AGRICULTURAL AND HORTICULTURAL USE | 株式会社エス・ディー・エス バイオテック (JP) | 2011-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130296271-A1 | Agri-Horticultural Pest Control Compositions Comprising 4-(3-Butynyl)Aminopyrimidine Derivatives | HCN1, HCN2, HCN3 | RAB9A 3469/4885HTT 890/4885SMN1; SMN2 3889/4885 |
| US-20120136150-A1 | 4-(3-Butynyl)Aminopyrimidine Derivatives as Pest Control Agents for Agricultural and Horticultural Use | CBR3, CBR1, HRH2 | RAB9A 4200/4885HTT 2572/4885SMN1; SMN2 4679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.