Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2726553 | 0.97 | MAP4K1 (0.31) | MAP4K1DGAT2 | |
| SCHEMBL2726566 | 0.95 | MAP4K1 (0.31) | MAP4K1DGAT2 | |
| SCHEMBL2723614 | 0.92 | MAP4K1 (0.32) | MAP4K1DGAT2 | |
| SCHEMBL212091 | 0.91 | MAP4K1 (0.33) | MAP4K1DGAT2 | |
| SCHEMBL213616 | 0.91 | MAP4K1 (0.34) | MAP4K1DGAT2 | |
| SCHEMBL213615 | 0.91 | MAP4K1 (0.34) | MAP4K1DGAT2 | |
| SCHEMBL213614 | 0.91 | MAP4K1 (0.34) | MAP4K1DGAT2 | |
| SCHEMBL2722343 | 0.90 | CTSK (0.36) | — | |
| SCHEMBL212268 | 0.89 | MAP4K1 (0.33) | MAP4K1 | |
| SCHEMBL2723892 | 0.88 | MAP4K1 (0.34) | MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8759374-B2 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. (US) | 2014-06-24 | — | — | US | disclosed |
| US-20120135964-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | QIAN XIANGPING (US) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135964-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | MYLK, MYH2, MYH10 | MAP4K1 1290/4885DGAT2 4413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.