Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 11/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | WNT1 | P04628 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.31 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.31 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.31 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2725700 | 1.00 | MAPK1 (0.34) | MAPK1RPS6KA1ABL1METWNT1 | |
| SCHEMBL2725228 | 1.00 | MAPK1 (0.34) | MAPK1RPS6KA1ABL1METWNT1 | |
| SCHEMBL212082 | 0.93 | NOTUM (0.35) | MAPK1RPS6KA1ABL1METWNT1 | |
| SCHEMBL210072 | 0.93 | NOTUM (0.35) | MAPK1RPS6KA1ABL1METWNT1 | |
| SCHEMBL210070 | 0.93 | NOTUM (0.35) | MAPK1RPS6KA1ABL1METWNT1 | |
| SCHEMBL210071 | 0.93 | NOTUM (0.35) | MAPK1RPS6KA1ABL1METWNT1 | |
| SCHEMBL211611 | 0.93 | NOTUM (0.35) | MAPK1RPS6KA1ABL1METWNT1 | |
| SCHEMBL211333 | 0.93 | NOTUM (0.35) | MAPK1RPS6KA1ABL1METWNT1 | |
| SCHEMBL211785 | 0.93 | PIN1 (0.36) | MAPK1RPS6KA1ABL1METWNT1 | |
| SCHEMBL2724097 | 0.93 | PIN1 (0.36) | MAPK1RPS6KA1ABL1METWNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120135964-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | QIAN XIANGPING (US) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135964-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | MYLK, MYH2, MYH10 | MAPK1 2926/4885RPS6KA1 3757/4885ABL1 956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.