SCHEMBL9609300

SCHEMBL9609300

COC(=O)c1ccc(-c2nc(-c3ccc(OC)cc3O)nc(-c3ccc4ncccc4c3O)n2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.46
HTT P42858 1/20 0.46
IDH1 O75874 1/20 0.43
NPC1 O15118 2/20 0.42
RAB9A P51151 1/20 0.42
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
EGFR P00533 1/20 0.41
PLA2G2A P14555 2/20 0.40
ESR1 P03372 1/20 0.39
THRA P10827 1/20 0.39
THRB P10828 1/20 0.39
VDR P11473 1/20 0.39
RXRA P19793 1/20 0.39
PPARG P37231 1/20 0.39
PPARD Q03181 1/20 0.39
PPARA Q07869 1/20 0.39
ESR2 Q92731 1/20 0.39
SYK P43405 2/20 0.39
MEN1 O00255 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9608464 0.89 HTT (0.47) ALOX15HTTNPC1RAB9AEGFR
SCHEMBL12228479 0.88 ALOX15 (0.57) ALOX15HTTIDH1NPC1RAB9A
SCHEMBL17917588 0.87 HTT (0.45) ALOX15HTTNPC1RAB9AEGFR
SCHEMBL9609270 0.86 EGFR (0.46) NPC1RAB9ACA1CA2EGFR
SCHEMBL12228431 0.84 NPC1 (0.55) IDH1NPC1RAB9ACA1CA2
SCHEMBL12228411 0.83 CA1 (0.57) HTTNPC1CA1CA2EGFR
SCHEMBL12228365 0.82 EGFR (0.60) HTTNPC1RAB9ACA1CA2
SCHEMBL9609244 0.81 MEN1 (0.54) ALOX15IDH1NPC1CA1CA2
SCHEMBL9608547 0.80 ALOX15 (0.46) ALOX15HTTNPC1RAB9AEGFR
SCHEMBL12228416 0.80 VDR (0.53) NPC1RAB9ACA1CA2EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160200933-A1 RESIN COMPOSITION, PROTECTIVE FILM FOR POLARIZING PLATE, POLARIZING PLATE, AND DISPLAY FUJIFILM CORPORATION (JP) 2016-07-14 US disclosed
US-8957140-B2 Triazine derivative, ultraviolet absorber, and resin composition FUJIFILM CORPORATION (JP) 2015-02-17 US disclosed
US-8748520-B2 Polycarbonate resin composition containing triazine compound and molded article using the same FUJIFILM CORPORATION (JP) 2014-06-10 US disclosed
US-8623990-B2 Polyester resin composition FUJIFILM CORPORATION (JP) 2014-01-07 US disclosed
US-20120301696-A1 POLYESTER RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-11-29 US disclosed
EP-2460799-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM Corporation (JP) 2012-06-06 EP disclosed
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-05-31 US disclosed
US-20110077331-A1 POLYCARBONATE RESIN COMPOSITION CONTAINING TRIAZINE COMPOUND AND MOLDED ARTICLE USING THE SAME FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION C1R, RPSA, H1-2 ALOX15 2823/4885HTT 1355/4885IDH1 3273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.