SCHEMBL9608511

SCHEMBL9608511

Cc1cc(-c2nc(-c3ccccc3O)nc(-c3ccccc3O)n2)cc(C(F)(F)F)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.48
LMNA P02545 2/20 0.48
HSD17B10 Q99714 3/20 0.47
TSHR P16473 4/20 0.46
ADORA3 P0DMS8 1/20 0.46
ALOX15 P16050 1/20 0.46
ADORA2A P29274 1/20 0.46
ADORA2B P29275 1/20 0.46
ADORA1 P30542 1/20 0.46
CHUK O15111 1/20 0.45
TXNRD1 Q16881 1/20 0.45
NOX4 Q9NPH5 1/20 0.45
KMT2A Q03164 5/20 0.44
MAPK1 P28482 4/20 0.44
KDM4E B2RXH2 4/20 0.44
ALDH1A1 P00352 3/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2C19 P33261 2/20 0.44
SMN1; SMN2 Q16637 3/20 0.42
MAPT P10636 7/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9608551 0.95 LMNA (0.44) POLBLMNAHSD17B10TSHRADORA3
SCHEMBL9609271 0.90 POLB (0.54) POLBLMNAHSD17B10TSHRADORA3
SCHEMBL12754989 0.87 CYP1A2 (0.46) POLBLMNATSHRADORA3ALOX15
SCHEMBL18267897 0.82 L3MBTL1 (0.48) POLBLMNAALDH1A1SMN1; SMN2MAPT
SCHEMBL12250342 0.82 NPC1 (0.45) POLBLMNAHSD17B10TSHRADORA3
SCHEMBL9608549 0.82 LMNA (0.47) POLBLMNAHSD17B10TSHRADORA3
SCHEMBL9608484 0.81 POLB (0.55) POLBLMNAHSD17B10TSHRADORA3
SCHEMBL9608470 0.81 CHUK (0.55) POLBLMNAHSD17B10TSHRADORA3
SCHEMBL9609240 0.81 NPC1 (0.49) POLBLMNAHSD17B10TSHRADORA3
SCHEMBL9609235 0.80 NOTUM (0.48) POLBLMNATSHRADORA3ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8957140-B2 Triazine derivative, ultraviolet absorber, and resin composition FUJIFILM CORPORATION (JP) 2015-02-17 US disclosed
US-8748520-B2 Polycarbonate resin composition containing triazine compound and molded article using the same FUJIFILM CORPORATION (JP) 2014-06-10 US disclosed
US-8623990-B2 Polyester resin composition FUJIFILM CORPORATION (JP) 2014-01-07 US disclosed
US-20120301696-A1 POLYESTER RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-11-29 US disclosed
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-05-31 US disclosed
US-20110077331-A1 POLYCARBONATE RESIN COMPOSITION CONTAINING TRIAZINE COMPOUND AND MOLDED ARTICLE USING THE SAME FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION C1R, RPSA, H1-2 POLB 246/4885LMNA 1414/4885HSD17B10 3077/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.