Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP7 | P09237 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9608592 | 0.85 | MAPT (0.36) | MAPTNAMPTMMP1MMP7MMP8 | |
| SCHEMBL12418314 | 0.80 | MAPT (0.43) | MAPTNAMPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL794330 | 0.78 | NPC1 (0.37) | MAPTNAMPTALDH1A1NPC1RAB9A | |
| SCHEMBL770325 | 0.76 | MMP8 (0.39) | MAPTNAMPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4350050 | 0.74 | TSHR (0.38) | MAPTALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL770853 | 0.73 | MMP8 (0.38) | MAPTALDH1A1CYP1A2NPC1RAB9A | |
| SCHEMBL770346 | 0.71 | MMP8 (0.40) | ALDH1A1CYP1A2CYP3A4CYP2C9TSHR | |
| SCHEMBL770784 | 0.70 | DRD2 (0.40) | NPC1RAB9ASMN1; SMN2CNR2DRD2 | |
| SCHEMBL9608599 | 0.70 | HSD11B1 (0.37) | NAMPTTSHRCNR2DRD2 | |
| SCHEMBL9609290 | 0.70 | MAPT (0.35) | MAPTNAMPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120135348-A1 | ACTINIC-RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, ACTINIC-RAY-SENSITIVE OR RADIATION-SENSITIVE FILM, AND PATTERN FORMING METHOD | FUJIFILM CORPORATION (JP) | 2012-05-31 | — | — | US | disclosed |