SCHEMBL9608599

SCHEMBL9608599

O=S(=O)(O)CS(=O)(=O)N1CCC2CCCCC2C1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.37
HTR7 P34969 4/20 0.34
HTR1A P08908 2/20 0.33
HTR2A P28223 2/20 0.33
TSHR P16473 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
GAA P10253 1/20 0.33
USP5 P45974 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
NAMPT P43490 1/20 0.33
CNR2 P34972 5/20 0.32
DRD2 P14416 1/20 0.32
KMT2A Q03164 1/20 0.31
SLC18A3 Q16572 1/20 0.31
EPHX2 P34913 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9608588 0.84 KMT2A (0.36) HSD11B1HTR7HTR1AHTR2ATSHR
SCHEMBL22930966 0.81 TSHR (0.44) HTR7HTR1AHTR2ATSHRL3MBTL1
SCHEMBL15935686 0.76 HSD11B1 (0.37) HSD11B1HTR7USP5HDAC6NAMPT
SCHEMBL771112 0.75 ITGB3 (0.39) HSD11B1HTR7TSHRL3MBTL1GAA
SCHEMBL770329 0.72 HTR7 (0.39) HSD11B1HTR7HTR1AHTR2ATSHR
SCHEMBL9608594 0.72 CA1 (0.40) TSHRL3MBTL1KMT2A
SCHEMBL12303231 0.71 ALDH1A1 (0.42) HSD11B1TSHRGAA
SCHEMBL770553 0.70 KMT2A (0.40) TSHRL3MBTL1GAAKMT2AEPHX2
SCHEMBL9608600 0.70 MAPT (0.36) TSHRNAMPTCNR2DRD2
SCHEMBL9608593 0.70 CA1 (0.44) TSHRL3MBTL1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120135348-A1 ACTINIC-RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, ACTINIC-RAY-SENSITIVE OR RADIATION-SENSITIVE FILM, AND PATTERN FORMING METHOD FUJIFILM CORPORATION (JP) 2012-05-31 US disclosed