SCHEMBL279256

SCHEMBL279256

Cc1ccc(C(=Cc2ccc(N(c3ccc(CCC4CO4)cc3)c3ccc(CCC4CO4)cc3)cc2)c2ccc(C3CO3)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 2/20 0.36
TP53 P04637 1/20 0.34
ALOX5 P09917 1/20 0.33
CHRM2 P08172 1/20 0.31
CHRM5 P08912 1/20 0.31
CHRM3 P20309 1/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
ALDH1A1 P00352 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13313028 1.00 PTGS2 (0.36) PTGS2TP53ALOX5CHRM2CHRM5
SCHEMBL9607505 0.96 TP53 (0.36) PTGS2TP53ALOX5
SCHEMBL279561 0.83 PTGS2 (0.41) PTGS2TP53MEN1KMT2AALDH1A1
SCHEMBL9608744 0.80 TP53 (0.38) PTGS2TP53MEN1KMT2AALDH1A1
SCHEMBL278979 0.76 TSHR (0.44) PTGS2ALDH1A1
SCHEMBL9098089 0.76 PTGS2 (0.46) PTGS2TP53MEN1KMT2AALDH1A1
SCHEMBL13337948 0.76 SMN1; SMN2 (0.43) PTGS2TP53MEN1KMT2AALDH1A1
SCHEMBL15038792 0.75 PTGS2 (0.49) PTGS2ALOX5MEN1KMT2AALDH1A1
SCHEMBL15038441 0.75 PTGS2 (0.49) PTGS2ALOX5MEN1KMT2AALDH1A1
SCHEMBL443217 0.74 PTGS2 (0.57) PTGS2MEN1KMT2AALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8426093-B2 photosensitive layer has a charge transferring compound having hole transportation ability; hardening by heating, stable electrical properties FUJI XEROX CO., LTD. (JP) 2013-04-23 US disclosed
US-8426093-B2 photosensitive layer has a charge transferring compound having hole transportation ability; hardening by heating, stable electrical properties FUJI XEROX CO., LTD. (JP) 2013-04-23 US disclosed
US-8263299-B2 Multilayer; electroconductive support, photosensitive layer of cured phenolic resin having dynamics hardness and elastic deformation; xerography;thin film with few defects;mechanical strength; stability; high quality images FUJI XEROX CO., LTD. (JP) 2012-09-11 US disclosed
US-8263299-B2 Multilayer; electroconductive support, photosensitive layer of cured phenolic resin having dynamics hardness and elastic deformation; xerography;thin film with few defects;mechanical strength; stability; high quality images FUJI XEROX CO., LTD. (JP) 2012-09-11 US disclosed
US-8133645-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-03-13 US disclosed
US-8133645-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-03-13 US disclosed
US-8110328-B2 Conductive support with photosensitive layer containing curable resin, fluorinated surfactants and charge transfer compound FUJI XEROX CO., LTD. (JP) 2012-02-07 US disclosed
US-8110328-B2 Conductive support with photosensitive layer containing curable resin, fluorinated surfactants and charge transfer compound FUJI XEROX CO., LTD. (JP) 2012-02-07 US disclosed
US-7951516-B2 photographic and electrophotographic apparatus having cylindrical supports, charge generating and charge transporting layers and protective coatings comprising curable resins and thermoplastic resins; durability FUJI XEROX CO., LTD. (JP) 2011-05-31 US disclosed
US-7951516-B2 photographic and electrophotographic apparatus having cylindrical supports, charge generating and charge transporting layers and protective coatings comprising curable resins and thermoplastic resins; durability FUJI XEROX CO., LTD. (JP) 2011-05-31 US disclosed
US-20080102389-A1 Electrophotographic photoreceptor, method of producing the same, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2008-05-01 US disclosed
US-20080102389-A1 Electrophotographic photoreceptor, method of producing the same, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2008-05-01 US disclosed
US-20080102390-A1 Electrophotographic photoreceptor, method of producing the same, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2008-05-01 US disclosed
US-20080031642-A1 Electrophotographic photoreceptor, image forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2008-02-07 US disclosed
US-20070231721-A1 Electrophotographic photoreceptor, process cartridge, image forming apparatus and coating composition FUJI XEROX CO., LTD. (JP) 2007-10-04 US disclosed
US-20070231721-A1 Electrophotographic photoreceptor, process cartridge, image forming apparatus and coating composition FUJI XEROX CO., LTD. (JP) 2007-10-04 US disclosed
US-20070065741-A1 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2007-03-22 US disclosed
US-20070065741-A1 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2007-03-22 US disclosed
US-20070003850-A1 Curable resin composition, electrophotographic photoreceptor, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2007-01-04 US disclosed
US-20070003850-A1 Curable resin composition, electrophotographic photoreceptor, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2007-01-04 US disclosed