SCHEMBL9609338

SCHEMBL9609338

COC(=O)c1ccc(-c2nc(=O)c3cc(OC)ccc3o2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 11/20 0.57
SMN1; SMN2 Q16637 6/20 0.57
RAB9A P51151 5/20 0.57
KDM4E B2RXH2 5/20 0.57
ALDH1A1 P00352 5/20 0.57
HPGD P15428 5/20 0.57
HSD17B10 Q99714 4/20 0.57
NPC1 O15118 4/20 0.57
TP53 P04637 4/20 0.56
NFKB1 P19838 2/20 0.54
NFKB2 Q00653 2/20 0.54
RELA Q04206 2/20 0.54
ATM Q13315 1/20 0.54
HDAC6 Q9UBN7 2/20 0.54
THRB P10828 3/20 0.52
TNKS O95271 1/20 0.49
HTT P42858 1/20 0.49
HSPD1 P10809 1/20 0.48
PTPN2 P17706 1/20 0.48
PTPN1 P18031 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9609212 0.91 MAPT (0.57) MAPTSMN1; SMN2RAB9AKDM4EALDH1A1
SCHEMBL9608575 0.87 VDR (0.53) MAPTSMN1; SMN2RAB9AKDM4EALDH1A1
SCHEMBL9608562 0.87 RAB9A (0.68) MAPTSMN1; SMN2RAB9AKDM4EALDH1A1
SCHEMBL9608564 0.86 MAPT (0.57) MAPTSMN1; SMN2RAB9AKDM4EALDH1A1
SCHEMBL17254744 0.84 ALDH1A1 (0.48) MAPTSMN1; SMN2RAB9AKDM4EALDH1A1
SCHEMBL9608566 0.84 MAPT (0.65) MAPTSMN1; SMN2RAB9AKDM4EALDH1A1
SCHEMBL9608554 0.84 MAPT (0.71) MAPTSMN1; SMN2RAB9AKDM4EALDH1A1
SCHEMBL9608557 0.80 MAPT (0.72) MAPTSMN1; SMN2RAB9AKDM4EALDH1A1
SCHEMBL7795159 0.77 MAOB (0.58) MAPTSMN1; SMN2RAB9AKDM4EALDH1A1
SCHEMBL9609310 0.76 MAPT (0.54) MAPTSMN1; SMN2RAB9AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8957140-B2 Triazine derivative, ultraviolet absorber, and resin composition FUJIFILM CORPORATION (JP) 2015-02-17 US disclosed
US-8748520-B2 Polycarbonate resin composition containing triazine compound and molded article using the same FUJIFILM CORPORATION (JP) 2014-06-10 US disclosed
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-05-31 US disclosed
US-8044123-B2 Ultraviolet absorber composition and resin composition FUJIFILM CORPORATION (JP) 2011-10-25 US disclosed
US-8044123-B2 Ultraviolet absorber composition and resin composition FUJIFILM CORPORATION (JP) 2011-10-25 US disclosed
US-20110077331-A1 POLYCARBONATE RESIN COMPOSITION CONTAINING TRIAZINE COMPOUND AND MOLDED ARTICLE USING THE SAME FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
US-20110077330-A1 POLYCARBONATE RESIN COMPOSITION CONTAINING TRIAZINE COMPOUND AND MOLDED ARTICLE USING THE SAME FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
US-20100324181-A1 ULTRAVIOLET ABSORBER COMPOSITION AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2010-12-23 US disclosed
US-20100324181-A1 ULTRAVIOLET ABSORBER COMPOSITION AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2010-12-23 US disclosed
US-20100311877-A1 NOVEL TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2010-12-09 US disclosed
US-20100311877-A1 NOVEL TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2010-12-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION C1R, RPSA, H1-2 MAPT 1774/4885SMN1; SMN2 3721/4885RAB9A 2727/4885
US-20100311877-A1 NOVEL TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION AVPR1B, H1-0, H1-2 MAPT 2637/4885SMN1; SMN2 3996/4885RAB9A 2649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.