Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | PGD | P52209 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10002061 | 1.00 | TSHR (0.45) | TSHRPGDCYP2C9PDE4ATP53 | |
| SCHEMBL9609680 | 1.00 | TSHR (0.45) | TSHRPGDCYP2C9PDE4ATP53 | |
| SCHEMBL2616762 | 1.00 | TSHR (0.45) | TSHRPGDCYP2C9PDE4ATP53 | |
| SCHEMBL17693480 | 1.00 | TSHR (0.45) | TSHRPGDCYP2C9PDE4ATP53 | |
| SCHEMBL3453885 | 0.79 | TSHR (0.45) | TSHRPGDCYP2C9PDE4ATP53 | |
| SCHEMBL28150772 | 0.77 | TSHR (0.43) | TSHRPGDCYP2C9PDE4A | |
| SCHEMBL28163286 | 0.77 | TSHR (0.43) | TSHRPGDCYP2C9PDE4A | |
| SCHEMBL13017376 | 0.76 | — | — | |
| SCHEMBL13017377 | 0.76 | — | — | |
| SCHEMBL15859132 | 0.75 | TSHR (0.41) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170151145-A1 | POWERFUL HAIR TREATMENT AGENT HAVING ANTI-WASHOUT EFFECT | HENKEL AG & CO. KGAA (DE) | 2017-06-01 | — | — | US | disclosed |
| US-20170151153-A1 | POWERFUL HAIR TREATMENT AGENT WITH ANTI-WASHOUT EFFECT | HENKEL AG & CO. KGAA (DE) | 2017-06-01 | — | — | US | disclosed |
| US-20120277433-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED QUINOXALINES | ALKEM LABORATORIES LIMITED (IN) | 2012-11-01 | — | — | US | disclosed |
| US-20120136096-A1 | PROTECTION OF A DISPERSING AGENT DURING A GRINDING OPERATION | LAFARGE (FR) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170151145-A1 | POWERFUL HAIR TREATMENT AGENT HAVING ANTI-WASHOUT EFFECT | OAT, HOGA1, LGALS7; LGALS7B | TSHR 2728/4885PGD 60/4885CYP2C9 4455/4885 |
| US-20170151153-A1 | POWERFUL HAIR TREATMENT AGENT WITH ANTI-WASHOUT EFFECT | SLC25A13, HOGA1, GCDH | TSHR 2420/4885PGD 41/4885CYP2C9 4204/4885 |
| US-20120277433-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED QUINOXALINES | QDPR, DCXR, NQO2 | TSHR 4398/4885PGD 821/4885CYP2C9 576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.