SCHEMBL9609741

SCHEMBL9609741

CCO[Si](CCCNCc1ccc2nccnc2c1)(OCC)OCC

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SHMT2 P34897 1/20 0.39
LMNA P02545 1/20 0.38
POLB P06746 4/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
MAPT P10636 1/20 0.37
THRB P10828 2/20 0.36
KDM4E B2RXH2 4/20 0.36
TDP1 Q9NUW8 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
HRH4 Q9H3N8 1/20 0.35
HRH3 Q9Y5N1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29151552 0.82 PDCD1 (0.41) LMNAPOLBTHRBKDM4ETDP1
SCHEMBL6762944 0.82 HRH4 (0.49) SHMT2LMNAKDM4ESMN1; SMN2HRH4
SCHEMBL9609747 0.79 MAPT (0.34) SHMT2POLBMEN1KMT2AMAPT
SCHEMBL13029177 0.79 HRH4 (0.57) LMNAPOLBMEN1KMT2ATHRB
SCHEMBL9609754 0.78 FAAH (0.41) LMNAPOLBMEN1KMT2AMAPT
SCHEMBL9609695 0.78 TERT (0.46) MAPT
SCHEMBL5697097 0.77 CHRM2 (0.57) LMNAMEN1KMT2ATHRBKDM4E
SCHEMBL9609748 0.77 ALOX5 (0.33) SHMT2POLBMEN1KMT2AMAPT
SCHEMBL9609725 0.77 MC5R (0.57)
SCHEMBL6656895 0.76 KDM4E (0.43) LMNAPOLBMEN1KMT2ATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8921243-B2 Fabrics comprising a photocatalyst to produce singlet oxygen from ambient oxygen VENTANA RESEARCH CORPORATION 2014-12-30 US disclosed
US-8481446-B2 Chemically-resistant coating composition VENTANA RESEARCH CORPORATION 2013-07-09 US disclosed
US-20120135651-A1 Fabrics Comprising a Photocatalyst to Produce Singlet Oxygen from Ambient Oxygen VENTANA RESEARCH CORPORATION 2012-05-31 US disclosed
US-20100279850-A1 CHEMICALLY-RESISTANT COATING COMPOSITION VENTANA RESEARCH CORPORATION 2010-11-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100279850-A1 CHEMICALLY-RESISTANT COATING COMPOSITION DNMT1, VCL, DNMT3L SHMT2 520/4885LMNA 549/4885POLB 1463/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.