SCHEMBL9609754

SCHEMBL9609754

CCO[Si](CCCNC(=O)OCc1ccc2nccnc2c1)(OCC)OCC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.41
MAPT P10636 4/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
HTT P42858 1/20 0.39
POLB P06746 3/20 0.38
KDM4E B2RXH2 3/20 0.38
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
ALDH1A1 P00352 2/20 0.38
KEAP1 Q14145 1/20 0.38
NFE2L2 Q16236 1/20 0.38
HPGD P15428 1/20 0.37
RAB9A P51151 3/20 0.37
NPC1 O15118 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
GAA P10253 1/20 0.37
CYP2D6 P10635 1/20 0.36
EPHX2 P34913 1/20 0.36
GLA P06280 1/20 0.36
TGM2 P21980 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6537376 0.83 HTT (0.44) FAAHMAPTL3MBTL1HTTKEAP1
SCHEMBL9609731 0.81 TGM2 (0.47) FAAHMAPTL3MBTL1HTTKEAP1
SCHEMBL2145355 0.79 HTT (0.62) FAAHMAPTL3MBTL1HTTKEAP1
SCHEMBL28520516 0.79 HTT (0.48) FAAHMAPTL3MBTL1HTTALDH1A1
SCHEMBL9609741 0.78 SHMT2 (0.39) MAPTPOLBKDM4EKMT2AMEN1
SCHEMBL9609737 0.78 HTT (0.43) FAAHMAPTL3MBTL1HTTALDH1A1
SCHEMBL13789649 0.78 HTT (0.44) FAAHMAPTL3MBTL1HTTKMT2A
SCHEMBL9609748 0.77 ALOX5 (0.33) MAPTL3MBTL1POLBKDM4EKMT2A
SCHEMBL462315 0.76 TOP2A (0.46) MAPTL3MBTL1POLBKDM4EKMT2A
SCHEMBL462314 0.76 ECE2 (0.43) MAPTL3MBTL1POLBKDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8921243-B2 Fabrics comprising a photocatalyst to produce singlet oxygen from ambient oxygen VENTANA RESEARCH CORPORATION 2014-12-30 US disclosed
US-8481446-B2 Chemically-resistant coating composition VENTANA RESEARCH CORPORATION 2013-07-09 US disclosed
US-20120135651-A1 Fabrics Comprising a Photocatalyst to Produce Singlet Oxygen from Ambient Oxygen VENTANA RESEARCH CORPORATION 2012-05-31 US disclosed
US-20100279850-A1 CHEMICALLY-RESISTANT COATING COMPOSITION VENTANA RESEARCH CORPORATION 2010-11-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100279850-A1 CHEMICALLY-RESISTANT COATING COMPOSITION DNMT1, VCL, DNMT3L FAAH 4164/4885MAPT 284/4885L3MBTL1 1230/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.