SCHEMBL9611240

SCHEMBL9611240

CCO[Si](CCCSCc1ccn(CC(=O)OC)c(=O)c1)(OCC)OCC

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 2/20 0.33
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 1/20 0.32
NPC1 O15118 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MAPT P10636 1/20 0.31
MEN1 O00255 1/20 0.31
RAB9A P51151 1/20 0.31
KMT2A Q03164 1/20 0.31
HDAC6 Q9UBN7 1/20 0.30
KAT2B Q92831 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9611243 0.84 ALDH1A1 (0.34) PDE10AALDH1A1KDM4ENPC1HSD17B10
SCHEMBL9611264 0.80 PLA2G7 (0.35)
SCHEMBL9611244 0.79 NPC1 (0.34) ALDH1A1KDM4ENPC1HSD17B10MEN1
SCHEMBL16382487 0.79 KDM4E (0.35) PDE10AALDH1A1KDM4EHSD17B10MAPT
SCHEMBL12187300 0.72 PLA2G7 (0.33)
SCHEMBL13029268 0.68 PSMB5 (0.42) ALDH1A1KDM4EHSD17B10MAPTKMT2A
SCHEMBL13086993 0.68 KDM4E (0.32) ALDH1A1KDM4ENPC1HSD17B10MEN1
SCHEMBL9611265 0.68 BMPR1B (0.30)
SCHEMBL13029170 0.67 LMNA (0.33) ALDH1A1NPC1MAPTRAB9A
SCHEMBL10178811 0.67 TSHR (0.39) ALDH1A1HSD17B10MEN1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8921243-B2 Fabrics comprising a photocatalyst to produce singlet oxygen from ambient oxygen VENTANA RESEARCH CORPORATION 2014-12-30 US disclosed
US-8481446-B2 Chemically-resistant coating composition VENTANA RESEARCH CORPORATION 2013-07-09 US disclosed
US-20120135651-A1 Fabrics Comprising a Photocatalyst to Produce Singlet Oxygen from Ambient Oxygen VENTANA RESEARCH CORPORATION 2012-05-31 US disclosed
US-20100279850-A1 CHEMICALLY-RESISTANT COATING COMPOSITION VENTANA RESEARCH CORPORATION 2010-11-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100279850-A1 CHEMICALLY-RESISTANT COATING COMPOSITION DNMT1, VCL, DNMT3L PDE10A 4837/4885ALDH1A1 1103/4885KDM4E 173/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.