Sugi Predict

Sugi Predict / Compounds / SCHEMBL9611245

SCHEMBL9611245

SCHEMBL9611245

OCc1c2ccccc2nc2ccccc12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 8/20 0.57
▸ ALDH1A1 P00352 5/20 0.57
▸ GAA P10253 3/20 0.57
▸ HPGD P15428 3/20 0.57
▸ GLA P06280 5/20 0.55
▸ POLB P06746 5/20 0.52
▸ RAD52 P43351 4/20 0.52
▸ RAB9A P51151 3/20 0.52
▸ LMNA P02545 2/20 0.52
▸ MITF O75030 1/20 0.52
▸ TTR P02766 1/20 0.52
▸ MAOA P21397 2/20 0.50
▸ CASP1 P29466 2/20 0.50
▸ CASP7 P55210 2/20 0.50
▸ SMN1; SMN2 Q16637 2/20 0.50
▸ HSD17B10 Q99714 2/20 0.50
▸ CHRM2 P08172 1/20 0.50
▸ ADRA2A P08913 1/20 0.50
▸ ADORA3 P0DMS8 1/20 0.50
▸ CHRM1 P11229 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3347485 0.82 KDM4E (0.64) KDM4EALDH1A1GAAHPGDGLA
SCHEMBL3970688 0.81 PDE10A (0.56) KDM4EALDH1A1GAAHPGDGLA
SCHEMBL9271510 0.81 MAOA (0.46) KDM4EALDH1A1GAAHPGDGLA
SCHEMBL29446776 0.80 KDM4E (0.75) KDM4EALDH1A1GAAHPGDGLA
SCHEMBL321444 0.80 KDM4E (0.75) KDM4EALDH1A1GAAHPGDGLA
SCHEMBL14130585 0.80 KDM4E (0.61) KDM4EALDH1A1GAAHPGDGLA
SCHEMBL29853841 0.79 TSHR (0.45) KDM4EALDH1A1GAAPOLBSMN1; SMN2
SCHEMBL488963 0.79 TSHR (0.45) KDM4EALDH1A1GAAPOLBSMN1; SMN2
SCHEMBL15414896 0.78 KDM4E (0.46) KDM4EALDH1A1GAAHPGDGLA
SCHEMBL12767717 0.78 ERN1 (0.54) KDM4EALDH1A1GAAHPGDGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110240564-A A kind of preparation method of 9- methylol-acridan 郑州原理生物科技有限公司 2019-09-17 — — CN claimed
US-8921243-B2 Fabrics comprising a photocatalyst to produce singlet oxygen from ambient oxygen VENTANA RESEARCH CORPORATION 2014-12-30 — — US disclosed
US-8481446-B2 Chemically-resistant coating composition VENTANA RESEARCH CORPORATION 2013-07-09 — — US disclosed
US-20120135651-A1 Fabrics Comprising a Photocatalyst to Produce Singlet Oxygen from Ambient Oxygen VENTANA RESEARCH CORPORATION 2012-05-31 — — US disclosed
WO-2011142838-A2 CHEMICALLY-RESISTANT COATING COMPOSITION LOMBARID JOHN L (US) 2011-11-17 — — WO disclosed
US-20100279850-A1 CHEMICALLY-RESISTANT COATING COMPOSITION VENTANA RESEARCH CORPORATION 2010-11-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100279850-A1 CHEMICALLY-RESISTANT COATING COMPOSITION DNMT1, VCL, DNMT3L KDM4E 173/4885ALDH1A1 1103/4885GAA 4144/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.