Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL964815 | 1.00 | LMNA (0.35) | LMNAL3MBTL1ALDH1A1TSHRPDE4A | |
| SCHEMBL5085107 | 0.95 | LMNA (0.39) | LMNAL3MBTL1ALDH1A1TSHRPDE4A | |
| SCHEMBL17870921 | 0.84 | ALDH1A1 (0.32) | ALDH1A1TSHRTHRB | |
| SCHEMBL23357664 | 0.83 | NAAA (0.41) | LMNAALDH1A1TSHRUSP2KDM4E | |
| SCHEMBL7540423 | 0.81 | LMNA (0.35) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL5689033 | 0.78 | LMNA (0.33) | LMNAL3MBTL1ALDH1A1PDE4ATDP1 | |
| SCHEMBL1133839 | 0.78 | PDE4A (0.50) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL4850735 | 0.76 | LMNA (0.34) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL5173596 | 0.76 | PDE4A (0.48) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL3899113 | 0.75 | LMNA (0.48) | LMNAL3MBTL1PDE4ATDP1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110021697-A1 | METHODS FOR PREPARING POLYETHER ESTER ELASTOMER COMPOSITION | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-01-27 | — | — | US | disclosed |
| WO-2008054777-A2 | POLYETHER ESTER ELASTOMER COMPOSITION | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-05-08 | — | — | WO | disclosed |
| US-20080103217-A1 | Polyether ester elastomer composition | E. I. DU PONT DE NEMOURS AND COMPANY | 2008-05-01 | — | — | US | disclosed |