Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 10/20 | 0.68 |
| ▸ | HTR7 | P34969 | 9/20 | 0.68 |
| ▸ | HTR1D | P28221 | 4/20 | 0.68 |
| ▸ | HTR2C | P28335 | 4/20 | 0.68 |
| ▸ | HTR2B | P41595 | 4/20 | 0.68 |
| ▸ | HTR5A | P47898 | 4/20 | 0.68 |
| ▸ | HTR6 | P50406 | 4/20 | 0.68 |
| ▸ | HTR2A | P28223 | 2/20 | 0.66 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 3/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18118440 | 0.88 | HTR1A (0.62) | HTR1AHTR7HTR1DHTR2CHTR2B | |
| SCHEMBL4685410 | 0.85 | MEN1 (0.60) | HTR1AHTR7ADRA1BDRD2ADRA1A | |
| SCHEMBL4938926 | 0.85 | MEN1 (0.60) | HTR1AHTR7ADRA1BDRD2ADRA1A | |
| SCHEMBL3200957 | 0.83 | HTR1A (0.62) | HTR1AHTR7HTR1DHTR2CHTR2B | |
| SCHEMBL4687871 | 0.83 | DRD2 (0.58) | HTR1AHTR7HTR5AHTR6HTR2A | |
| SCHEMBL4935832 | 0.83 | DRD2 (0.58) | HTR1AHTR7HTR5AHTR6HTR2A | |
| SCHEMBL5848982 | 0.82 | KCNH2 (0.75) | HTR1AHTR7HTR2ADRD2DRD3 | |
| SCHEMBL11030623 | 0.82 | HTR1A (0.73) | HTR1AHTR7HTR1DHTR2CHTR2B | |
| SCHEMBL18010427 | 0.81 | HTR7 (1.00) | HTR1AHTR7HTR1DHTR2CHTR2B | |
| SCHEMBL9612237 | 0.81 | MPO (0.61) | HTR1AHTR7HTR1DHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651411-B1 | METHODS AND COMPOSITIONS FOR IMPROVED F-18 LABELING OF PROTEINS, PEPTIDES AND OTHER MOLECULES | IMMUNOMEDICS INC (US) | 2020-09-16 | — | — | EP | disclosed |
| US-8758726-B2 | Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules | IMMUNOMEDICS, INC. (US) | 2014-06-24 | — | — | US | disclosed |
| US-20140017168-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. (US) | 2014-01-16 | — | — | US | disclosed |
| US-8545809-B2 | Methods and compositions for improved 18F labeling of proteins, peptides and other molecules | IMMUNOMEDICS, INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-20120134920-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. (US) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120134920-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | F13B, FCGRT, PAICS | HTR1A 4338/4885HTR7 4714/4885HTR1D 4109/4885 |
| US-20140017168-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | F13B, FCGRT, PAICS | HTR1A 4338/4885HTR7 4714/4885HTR1D 4109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.