Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 5/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | LAP3 | P28838 | 2/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL95928 | 0.83 | OPRM1 (0.41) | OPRM1SPHK1FAAHLMNACNR1 | |
| SCHEMBL5159088 | 0.83 | OPRM1 (0.41) | OPRM1SPHK1FAAHLMNACNR1 | |
| SCHEMBL17123786 | 0.81 | OPRM1 (0.42) | OPRM1SPHK1TP53CYP2D6LMNA | |
| SCHEMBL6903969 | 0.79 | TDP1 (0.52) | SPHK1TP53FAAHCYP2D6LMNA | |
| SCHEMBL26270570 | 0.79 | TDP1 (0.52) | SPHK1TP53FAAHCYP2D6LMNA | |
| SCHEMBL1276985 | 0.79 | HTT (0.49) | OPRM1SPHK1HTTDNM1 | |
| SCHEMBL114180 | 0.79 | HTT (0.49) | OPRM1SPHK1HTTDNM1 | |
| SCHEMBL10313070 | 0.79 | HTT (0.49) | OPRM1SPHK1HTTDNM1 | |
| SCHEMBL25142216 | 0.78 | OPRM1 (0.46) | OPRM1SPHK1FAAHCNR1CNR2 | |
| SCHEMBL22649557 | 0.78 | OPRM1 (0.50) | OPRM1SPHK1TP53FAAHLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170008922-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | AJINOMOTO CO., INC. (JP) | 2017-01-12 | — | — | US | disclosed |
| US-9499579-B2 | Branched chain-containing aromatic compound | AJINOMOTO CO., INC. (JP) | 2016-11-22 | — | — | US | disclosed |
| US-8546534-B2 | Branched chain-containing aromatic compound | AJINOMOTO CO., INC. (JP) | 2013-10-01 | — | — | US | disclosed |
| US-20120059149-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | AJINOMOTO CO. INC. (JP) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059149-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | VIP, BCAT2, IAPP | OPRM1 3849/4885SPHK1 3489/4885TP53 1974/4885 |
| US-20170008922-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | VIP, IAPP, BCAT1 | OPRM1 4125/4885SPHK1 3669/4885TP53 1648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.