SCHEMBL9612965

SCHEMBL9612965

Cc1cncc(-c2ccc(-c3c4ccccc4c(-c4cccc5c(C6CCCCC6)cccc45)c4ccccc34)cc2)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 3/20 0.37
PDK4 Q16654 2/20 0.37
PTGS2 P35354 5/20 0.37
CAMKK2 Q96RR4 4/20 0.35
APLNR P35414 1/20 0.35
PTPN5 P54829 2/20 0.33
PTPN2 P17706 1/20 0.33
PTGES O14684 1/20 0.33
PIK3CB P42338 1/20 0.33
PRKDC P78527 1/20 0.33
ATM Q13315 1/20 0.33
ATR Q13535 1/20 0.33
ATRIP Q8WXE1 1/20 0.33
GBA1 P04062 1/20 0.33
PDK1 Q15118 1/20 0.33
CASP3 P42574 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
CAMKK1 Q8N5S9 3/20 0.32
SGK1 O00141 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9612921 0.80 DHFR (0.40) GBA1
SCHEMBL9612928 0.80 CYP2A6 (0.38) GBA1
SCHEMBL18174764 0.78 CYP2A6 (0.41) PTGS2GBA1
SCHEMBL15161112 0.78 CYP2A6 (0.47) GBA1
SCHEMBL9613124 0.76 CAMKK1 (0.37) PTGS2CAMKK2PTPN5CAMKK1SGK1
SCHEMBL9612848 0.76 DHODH (0.41) PDK2PDK4PTGS2PTGESGBA1
SCHEMBL9612943 0.76 CYP2A6 (0.39) PTGS2GBA1
SCHEMBL9612978 0.75 PTGS2 (0.41) PDK2PDK4PTGS2CAMKK2CAMKK1
SCHEMBL15161047 0.74 CYP11B2 (0.43) GBA1
SCHEMBL18174777 0.73 CYP2A6 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012070535-A1 ELECTRON TRANSPORT MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME JNC株式会社 (JP) 2012-05-31 WO disclosed