Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC13A5 | Q86YT5 | 10/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.32 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10484293 | 0.89 | SLC13A5 (0.39) | SLC13A5KDM4ELMNAPDE10A | |
| Citric Acid SCHEMBL9613733 | 0.79 | SLC13A5 (0.40) | SLC13A5KDM4ELMNAPDE10ADHODH | |
| Citric Acid SCHEMBL10484280 | 0.71 | SLC13A5 (0.39) | SLC13A5KDM4ELMNAPDE10A | |
| SCHEMBL10484411 | 0.68 | SLC13A5 (0.53) | SLC13A5KDM4ELMNA | |
| SCHEMBL9613838 | 0.67 | SLC13A5 (0.41) | SLC13A5KDM4ELMNA | |
| SCHEMBL9291814 | 0.65 | PPARG (0.41) | HTR1BADRB2 | |
| Citric Acid SCHEMBL3986 | 0.64 | SLC6A4 (0.43) | SLC13A5 | |
| SCHEMBL9614062 | 0.63 | ALDH1A1 (0.50) | KDM4EHTR1B | |
| SCHEMBL14613949 | 0.62 | NCEH1 (0.42) | HTR1BNCEH1 | |
| Citric Acid SCHEMBL28294783 | 0.62 | LMNA (0.67) | SLC13A5KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5135947-A | Treatment of depression, eating disorders, and alcoholism | ELI LILLY AND COMPANY (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0288188-B1 | 1-PHENYL-3-NAPHTHALENYLOXY-PROPANAMINES | ELI LILLY AND COMPANY (US) | 1991-10-16 | — | — | EP | disclosed |