Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.33 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.33 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.33 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9614037 | 0.84 | HTR1B (0.45) | ALDH1A1MAPTHPGDMCL1BCL2 | |
| SCHEMBL10484268 | 0.80 | MCL1 (0.35) | KCNH2MMP3MEN1ALDH1A1KMT2A | |
| SCHEMBL9613811 | 0.74 | KDM4E (0.50) | ALDH1A1KMT2AHPGDMCL1BCL2 | |
| SCHEMBL9614067 | 0.73 | MCL1 (0.48) | ALDH1A1MAPTHPGDMCL1BCL2 | |
| SCHEMBL9613784 | 0.71 | ALDH1A1 (0.44) | ALDH1A1KMT2AMAPTHPGDNPC1 | |
| Oxalic Acid SCHEMBL9613749 | 0.70 | SCN4A (0.39) | KCNH2CXCR2MMP3MEN1KMT2A | |
| SCHEMBL9613953 | 0.70 | MCL1 (0.47) | ALDH1A1HPGDCYP1A2CYP2C19MCL1 | |
| SCHEMBL9291964 | 0.68 | KCNH2 (0.41) | KCNH2MMP3MEN1ALDH1A1KMT2A | |
| SCHEMBL9613906 | 0.67 | MCL1 (0.44) | ALDH1A1HPGDMCL1BCL2BCL2L1 | |
| SCHEMBL9613801 | 0.66 | HTR1B (0.45) | MEN1ALDH1A1KMT2AHPGDMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5135947-A | Treatment of depression, eating disorders, and alcoholism | ELI LILLY AND COMPANY (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0288188-B1 | 1-PHENYL-3-NAPHTHALENYLOXY-PROPANAMINES | ELI LILLY AND COMPANY (US) | 1991-10-16 | — | — | EP | disclosed |