Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9613850 | 0.91 | PPARG (0.45) | PPARGPPARAKMT2APTGES2MMP2 | |
| SCHEMBL9614319 | 0.86 | MMP2 (0.54) | PPARGPPARAKMT2AGAAALDH1A1 | |
| SCHEMBL9613878 | 0.84 | PPARA (0.47) | PPARGPPARAKMT2AMMP2MMP9 | |
| SCHEMBL9613829 | 0.83 | KMT2A (0.45) | PPARGPPARAKMT2AGAAALDH1A1 | |
| SCHEMBL9613989 | 0.83 | PPARA (0.43) | PPARGPPARAMMP2MMP9MAPT | |
| SCHEMBL9614321 | 0.82 | CA2 (0.41) | PPARGPPARA | |
| SCHEMBL9613899 | 0.80 | TAAR1 (0.47) | PPARGPPARAKMT2AALDH1A1MEN1 | |
| SCHEMBL9614049 | 0.78 | MMP2 (0.49) | PPARGPPARAKMT2AGAAALDH1A1 | |
| SCHEMBL9858523 | 0.77 | MMP2 (0.44) | KMT2AGAAALDH1A1CNR2MMP2 | |
| SCHEMBL27274785 | 0.77 | PPARA (0.47) | PPARGPPARAGAAALDH1A1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145611-A | Diabetes | BOEHRINGER MANNHEIM GMBH (DE) | 1992-09-08 | — | — | US | disclosed |