Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.49 |
| ▸ | MMP9 | P14780 | 4/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9613999 | 0.93 | FKBP1A (0.48) | MMP2MMP9CNR2KMT2APPARG | |
| SCHEMBL9614319 | 0.89 | MMP2 (0.54) | MMP2MMP9CNR2KMT2APPARG | |
| SCHEMBL9614069 | 0.89 | MMP9 (0.47) | MMP2MMP9CNR2KMT2AALDH1A1 | |
| SCHEMBL9614324 | 0.82 | MMP2 (0.46) | MMP2MMP9CNR2ALDH1A1LMNA | |
| SCHEMBL10419216 | 0.81 | MMP2 (0.59) | MMP2MMP9CNR2KMT2APPARG | |
| SCHEMBL10419184 | 0.81 | MMP2 (0.57) | MMP2MMP9CNR2KMT2APPARG | |
| SCHEMBL9858523 | 0.81 | MMP2 (0.44) | MMP2MMP9CNR2KMT2AEGFR | |
| SCHEMBL10420484 | 0.80 | MMP2 (0.56) | MMP2MMP9CNR2KMT2APPARG | |
| SCHEMBL865930 | 0.80 | MMP2 (0.56) | MMP2MMP9CNR2KMT2APPARG | |
| SCHEMBL10419952 | 0.80 | MMP2 (0.56) | MMP2MMP9CNR2KMT2APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145611-A | Diabetes | BOEHRINGER MANNHEIM GMBH (DE) | 1992-09-08 | — | — | US | disclosed |
| EP-0279162-B1 | CARBONIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1991-06-19 | — | — | EP | disclosed |
| EP-0279162-A1 | Carbonic acid derivatives, process for their preparation and pharmaceuticals containing them | Roche Diagnostics GmbH (DE) | 1988-08-24 | — | — | EP | disclosed |