Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3781054 | 0.82 | BCHE (0.41) | ALDH1A1LMNASMN1; SMN2HPGDMTOR | |
| SCHEMBL3507948 | 0.81 | CYP2A6 (0.51) | GAAHTTALDH1A1MAPTHSD17B10 | |
| SCHEMBL14889183 | 0.81 | ALDH1A1 (0.44) | HPGDSALKBH2GAAHTTALDH1A1 | |
| SCHEMBL10560658 | 0.75 | GAA (0.47) | HPGDSALKBH2GAAHTTCYP2C9 | |
| SCHEMBL3505282 | 0.75 | CYP11B1 (0.49) | HTTALDH1A1LMNARAB9A | |
| Hydrochloric Acid SCHEMBL10562627 | 0.73 | GAA (0.46) | HPGDSALKBH2GAAHTTCYP2C9 | |
| SCHEMBL2364050 | 0.73 | ROCK2 (0.32) | — | |
| SCHEMBL23909399 | 0.69 | HPGDS (0.46) | HPGDSALKBH2GAAHTTLMNA | |
| SCHEMBL3505817 | 0.69 | NCOA3 (0.50) | GAAHTTALDH1A1NPC1RAB9A | |
| SCHEMBL10563701 | 0.69 | HPGDS (0.45) | HPGDSALKBH2GAAHTTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169429-A | Using 4-oxo-1-phenyl-1,4-dihydropyridazine | MONSANTO COMPANY (US) | 1992-12-08 | — | — | US | disclosed |