Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 7/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9613892 | 0.69 | HPGDS (0.47) | HPGDSALKBH2GAARAB9ASMN1; SMN2 | |
| SCHEMBL515503 | 0.67 | GAA (0.59) | HPGDSALKBH2GAARAB9ASMN1; SMN2 | |
| SCHEMBL7044640 | 0.67 | HPGD (0.49) | RAB9ASMN1; SMN2HPGDLMNAKDM4E | |
| SCHEMBL1009561 | 0.66 | CYP2A6 (0.64) | GAASMN1; SMN2LMNAKDM4ENOTUM | |
| SCHEMBL11696626 | 0.65 | GAA (0.52) | HPGDSALKBH2GAARAB9ASMN1; SMN2 | |
| Formaldehyde SCHEMBL28266913 | 0.65 | SMN1; SMN2 (0.58) | HPGDSALKBH2GAASMN1; SMN2LMNA | |
| SCHEMBL9797100 | 0.65 | CYP3A4 (0.50) | GAARAB9ASMN1; SMN2HPGDLMNA | |
| SCHEMBL17736002 | 0.65 | GAA (0.57) | HPGDSALKBH2GAARAB9ASMN1; SMN2 | |
| SCHEMBL18016128 | 0.64 | ALKBH2 (0.74) | HPGDSALKBH2GAARAB9ASMN1; SMN2 | |
| SCHEMBL28006297 | 0.64 | CYP2A6 (0.62) | GAASMN1; SMN2LMNAKDM4ENOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230172981-A1 | METHODS AND COMPOSITIONS FOR STIMULATION OF CHIMERIC ANTIGEN RECEPTOR T CELLS WITH HAPTEN LABELLED CELLS | SEATTLE CHILDRENS HOSPITAL DBA SEATTLE CHILDRENS RES INST (US) | 2023-06-08 | — | — | US | disclosed |
| US-20210317407-A1 | METHODS AND COMPOSITIONS FOR STIMULATION OF CHIMERIC ANTIGEN RECEPTOR T CELLS WITH HAPTEN LABELLED CELLS | Seattle Children's Hospital (dba Seattle Children's Research Institute) | 2021-10-14 | — | — | US | disclosed |