Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 8/20 | 0.48 |
| ▸ | MMP13 | P45452 | 5/20 | 0.48 |
| ▸ | MMP2 | P08253 | 4/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9858467 | 0.95 | MMP9 (0.55) | MMP9MMP13MMP2MMP3ADAM17 | |
| SCHEMBL9613916 | 0.95 | MMP9 (0.52) | MMP9MMP13MMP2MMP3ADAM17 | |
| SCHEMBL10419485 | 0.94 | MMP9 (0.54) | MMP9MMP13MMP2MMP3ADAM17 | |
| SCHEMBL9614153 | 0.94 | MMP9 (0.46) | MMP9MMP13MMP2MMP3ADAM17 | |
| SCHEMBL9858481 | 0.94 | MMP2 (0.53) | MMP9MMP13MMP2MMP3MEN1 | |
| SCHEMBL10419451 | 0.93 | MMP2 (0.55) | MMP9MMP13MMP2MMP3MEN1 | |
| SCHEMBL9613940 | 0.88 | MMP9 (0.49) | MMP9MMP13MMP2MMP3ADAM17 | |
| SCHEMBL9613751 | 0.86 | MMP2 (0.47) | MMP9MMP13MMP2MMP3MEN1 | |
| SCHEMBL9614240 | 0.84 | MMP2 (0.46) | MMP9MMP13MMP2MMP3MEN1 | |
| SCHEMBL7825144 | 0.83 | MMP9 (0.55) | MMP9MMP13MMP2MMP3ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145611-A | Diabetes | BOEHRINGER MANNHEIM GMBH (DE) | 1992-09-08 | — | — | US | disclosed |
| EP-0279162-B1 | CARBONIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1991-06-19 | — | — | EP | disclosed |
| EP-0279162-A1 | Carbonic acid derivatives, process for their preparation and pharmaceuticals containing them | Roche Diagnostics GmbH (DE) | 1988-08-24 | — | — | EP | disclosed |