Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 8/20 | 0.53 |
| ▸ | MMP9 | P14780 | 7/20 | 0.53 |
| ▸ | MMP3 | P08254 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9613916 | 0.99 | MMP9 (0.52) | MMP2MMP9MMP3MMP13TDP1 | |
| SCHEMBL9614130 | 0.94 | MMP9 (0.48) | MMP2MMP9MMP3MMP13POLB | |
| SCHEMBL10419451 | 0.89 | MMP2 (0.55) | MMP2MMP9MMP3MMP13POLB | |
| SCHEMBL9858467 | 0.89 | MMP9 (0.55) | MMP2MMP9MMP3MMP13KMT2A | |
| SCHEMBL9614153 | 0.88 | MMP9 (0.46) | MMP2MMP9MMP3MMP13POLB | |
| SCHEMBL10419485 | 0.88 | MMP9 (0.54) | MMP2MMP9MMP3MMP13KMT2A | |
| SCHEMBL9614020 | 0.88 | MMP2 (0.51) | MMP2MMP9MMP3MMP13TDP1 | |
| SCHEMBL9613940 | 0.84 | MMP9 (0.49) | MMP2MMP9MMP3MMP13KMT2A | |
| SCHEMBL9614084 | 0.84 | PPARG (0.48) | MMP2MMP9KMT2AMEN1ALDH1A1 | |
| SCHEMBL9613976 | 0.82 | MMP2 (0.51) | MMP2MMP9MMP3MMP13TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279162-B1 | CARBONIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1991-06-19 | — | — | EP | disclosed |
| EP-0279162-A1 | Carbonic acid derivatives, process for their preparation and pharmaceuticals containing them | Roche Diagnostics GmbH (DE) | 1988-08-24 | — | — | EP | disclosed |