Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 8/20 | 0.55 |
| ▸ | MMP13 | P45452 | 6/20 | 0.55 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.55 |
| ▸ | MMP1 | P03956 | 3/20 | 0.55 |
| ▸ | MMP2 | P08253 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9614130 | 0.95 | MMP9 (0.48) | MMP9MMP13ADAM17MMP1MMP2 | |
| SCHEMBL9613916 | 0.90 | MMP9 (0.52) | MMP9MMP13ADAM17MMP1MMP2 | |
| SCHEMBL10419485 | 0.89 | MMP9 (0.54) | MMP9MMP13ADAM17MMP1MMP2 | |
| SCHEMBL9614153 | 0.89 | MMP9 (0.46) | MMP9MMP13ADAM17MMP1MMP2 | |
| SCHEMBL9858481 | 0.89 | MMP2 (0.53) | MMP9MMP13MMP2ALDH1A1LMNA | |
| SCHEMBL10419451 | 0.88 | MMP2 (0.55) | MMP9MMP13MMP2LMNANPC1 | |
| SCHEMBL10420433 | 0.87 | MMP1 (0.54) | MMP9MMP13ADAM17MMP1MMP2 | |
| SCHEMBL10420220 | 0.87 | MMP1 (0.54) | MMP9MMP13ADAM17MMP1MMP2 | |
| SCHEMBL9613940 | 0.86 | MMP9 (0.49) | MMP9MMP13ADAM17MMP1MMP2 | |
| SCHEMBL6928909 | 0.84 | MMP13 (0.75) | MMP9MMP13ADAM17MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279162-B1 | CARBONIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1991-06-19 | — | — | EP | disclosed |