Sugi Predict

Sugi Predict / Compounds / SCHEMBL9614829

SCHEMBL9614829

SCHEMBL9614829

Cn1cccc(C(N)=O)c1=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 4/20 0.44
▸ ALDH1A1 P00352 2/20 0.44
▸ SMN1; SMN2 Q16637 1/20 0.44
▸ PARP1 P09874 6/20 0.44
▸ MAPT P10636 1/20 0.42
▸ HPGD P15428 1/20 0.42
▸ TSHR P16473 1/20 0.42
▸ HSD17B10 Q99714 1/20 0.42
▸ IRAK4 Q9NWZ3 1/20 0.42
▸ METAP2 P50579 1/20 0.39
▸ ADRA1D P25100 1/20 0.39
▸ PARP2 Q9UGN5 3/20 0.39
▸ LMNA P02545 1/20 0.39
▸ HTT P42858 1/20 0.39
▸ MAP2K2 P36507 1/20 0.38
▸ MAP2K1 Q02750 1/20 0.38
▸ BCAT2 O15382 1/20 0.38
▸ RAB9A P51151 2/20 0.38
▸ NPC1 O15118 1/20 0.38
▸ KEAP1 Q14145 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3108319 0.82 KDM4E (0.45) KDM4EALDH1A1SMN1; SMN2PARP1MAPT
SCHEMBL2280624 0.82 ALDH1A1 (0.46) KDM4EALDH1A1SMN1; SMN2MAPTHPGD
SCHEMBL27667384 0.82 BRD4 (0.50) KDM4EALDH1A1SMN1; SMN2TSHRHSD17B10
SCHEMBL27189359 0.80 ALDH1A1 (0.41) KDM4EALDH1A1SMN1; SMN2MAPTHPGD
Hydrochloric Acid SCHEMBL17597430 0.80 ALDH1A1 (0.44) KDM4EALDH1A1SMN1; SMN2MAPTHPGD
SCHEMBL31667256 0.78 BRD4 (0.40) KDM4EALDH1A1SMN1; SMN2MAPTHPGD
SCHEMBL21812532 0.78 KDM4E (0.41) KDM4EALDH1A1SMN1; SMN2PARP1MAPT
SCHEMBL2284288 0.77 BRD4 (0.54) KDM4EALDH1A1SMN1; SMN2MAPTTSHR
SCHEMBL16982382 0.77 CNR2 (0.54) KDM4EALDH1A1SMN1; SMN2PARP1MAPT
SCHEMBL22723993 0.77 BRD4 (0.50) KDM4EALDH1A1PARP1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3436461-B1 PYRROLOTRIAZINE COMPOUNDS AS TAM INHIBITORS INCYTE CORP (US) 2023-11-01 — — EP claimed
CN-110520127-B Piperidinyl-substituted and piperazinyl-substituted heteroaromatic carboxamides as modulators of GPR6 武田药品工业株式会社 2023-05-16 — — CN claimed
EP-2838531-B1 INDOLIN-2-ONE DERIVATIVES AS PROTEIN KINASE INHIBITORS ANNJI PHARM CO LTD (CN) 2016-09-21 — — EP claimed
US-8946282-B2 Indolin-2-one derivatives as protein kinase inhibitors Annji Pharmaceutical Co., Ltd. (TW) 2015-02-03 — — US claimed
US-20130281451-A1 INDOLIN-2-ONE DERIVATIVES AS PROTEIN KINASE INHIBITORS Annji Pharmaceutical Co., Ltd. (TW) 2013-10-24 — — US claimed
US-20260015327-A1 ACYLSULFONAMIDE KAT6A INHIBITORS OLEMA PHARMACEUTICALS INC (US) 2026-01-15 — — US disclosed
US-12428379-B2 Acylsulfonamide KAT6A inhibitors OLEMA PHARMACEUTICALS, INC. (US) 2025-09-30 — — US disclosed
CN-113166094-B Compounds as protein kinase inhibitors and pharmaceutical compositions comprising the same 怡诺安有限公司 2025-05-06 — — CN disclosed
US-20250136553-A1 ACYLSULFONAMIDE KAT6A INHIBITORS OLEMA PHARMACEUTICALS, INC. 2025-05-01 — — US disclosed
US-12240862-B2 Inhibitors of peptidylarginine deiminases GILEAD SCIENCES, INC. (US) 2025-03-04 — — US disclosed
CN-117777103-A Amide compound and application thereof 和记黄埔医药（上海）有限公司 2024-03-29 — — CN disclosed
CN-117720519-A Amide compound and application thereof 和记黄埔医药（上海）有限公司 2024-03-19 — — CN disclosed
EP-2838531-B1 INDOLIN-2-ONE DERIVATIVES AS PROTEIN KINASE INHIBITORS ANNJI PHARM CO LTD (CN) 2016-09-21 — — EP disclosed
CN-103534254-B Tricyclic and tetracyclic pyrazolo [3,4-b ] pyridine compounds as antitumor agents PIERRE FABRE MEDICAMENT (FR) 2015-11-25 — — CN disclosed
US-8946282-B2 Indolin-2-one derivatives as protein kinase inhibitors Annji Pharmaceutical Co., Ltd. (TW) 2015-02-03 — — US disclosed
US-20130281451-A1 INDOLIN-2-ONE DERIVATIVES AS PROTEIN KINASE INHIBITORS Annji Pharmaceutical Co., Ltd. (TW) 2013-10-24 — — US disclosed
CN-101677549-A Use of pyridine-2-oxy-3-carboxamides as safeners BAYER CROPSCIENCE AG 2010-03-24 — — CN disclosed
CN-101522687-A Heterobicyclic thiophene compounds and methods of use ARRAY BIOPHARMA INC (US) 2009-09-02 — — CN disclosed
EP-0474654-A1 WATER SOLUBLE, FIBRE-REACTIVE DYES, PROCESS FOR MANUFACTURING THEM AND THEIR USE. HOECHST AG (DE) 1992-03-18 — — EP disclosed
EP-0204335-A2 2(1H)-Pyridin-ones useful as intermediates STERLING DRUG INC. (US) 1986-12-10 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250136553-A1 ACYLSULFONAMIDE KAT6A INHIBITORS KAT6A, KAT2A, KAT6B KDM4E 528/4885ALDH1A1 2242/4885SMN1; SMN2 1852/4885
US-12428379-B2 Acylsulfonamide KAT6A inhibitors KAT6A, KAT2A, KAT6B KDM4E 528/4885ALDH1A1 2242/4885SMN1; SMN2 1852/4885
US-20260015327-A1 ACYLSULFONAMIDE KAT6A INHIBITORS KAT6A, KAT2A, KAT6B KDM4E 773/4885ALDH1A1 1068/4885SMN1; SMN2 3098/4885
US-20130281451-A1 INDOLIN-2-ONE DERIVATIVES AS PROTEIN KINASE INHIBITORS ING2, CDK2, MAP3K20 KDM4E 2204/4885ALDH1A1 3369/4885SMN1; SMN2 4172/4885
US-12240862-B2 Inhibitors of peptidylarginine deiminases PADI4, PADI2, PADI1 KDM4E 936/4885ALDH1A1 2537/4885SMN1; SMN2 2054/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.