Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | SUMO2 | P61956 | 2/20 | 0.43 |
| ▸ | SUMO1 | P63165 | 2/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.43 |
| ▸ | SENP2 | Q9HC62 | 2/20 | 0.43 |
| ▸ | NQO1 | P15559 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6472138 | 0.89 | AURKA (0.41) | AURKAAURKBSUMO2SUMO1SENP7 | |
| SCHEMBL9614841 | 0.81 | TTR (0.50) | AURKAAURKBSUMO2SUMO1SENP7 | |
| SCHEMBL3205852 | 0.77 | AURKA (0.57) | AURKAAURKBCYP1A2CTRB1ALDH1A1 | |
| SCHEMBL27800252 | 0.77 | AURKA (0.50) | AURKAAURKBSUMO2SUMO1SENP7 | |
| SCHEMBL1755221 | 0.76 | TTR (0.49) | AURKAAURKBSUMO2SUMO1SENP7 | |
| SCHEMBL19569832 | 0.76 | CYP1A2 (0.59) | AURKAAURKBSUMO2SUMO1SENP7 | |
| SCHEMBL10881186 | 0.75 | AURKA (0.49) | AURKAAURKBSUMO2SUMO1SENP7 | |
| SCHEMBL10437095 | 0.75 | SUMO2 (0.63) | AURKAAURKBSUMO2SUMO1SENP7 | |
| SCHEMBL9680157 | 0.74 | AURKA (0.47) | AURKAAURKBSUMO2SUMO1SENP7 | |
| SCHEMBL7027692 | 0.74 | AURKA (0.53) | AURKAAURKBSUMO2SUMO1SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238458-A1 | COMPOUNDS TARGETING FIBROBLAST-ACTIVATION PROTEIN AND METHODS OF USE THEREOF | PURDUE RESEARCH FOUNDATION | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240238458-A1 | COMPOUNDS TARGETING FIBROBLAST-ACTIVATION PROTEIN AND METHODS OF USE THEREOF | FAP, FIBP, FGFR1 | AURKA 2308/4885AURKB 1635/4885SUMO2 3456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.