Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17486942 | 0.88 | ENPP2 (0.54) | PTGDR2ENPP2 | |
| SCHEMBL9615094 | 0.87 | PTGDR2 (0.57) | PTGDR2HDAC10HDAC6ENPP2 | |
| SCHEMBL9615138 | 0.86 | HDAC6 (0.64) | PTGDR2HDAC10HDAC6 | |
| SCHEMBL8804790 | 0.79 | BCHE (0.56) | HDAC6 | |
| SCHEMBL19132555 | 0.79 | PTGDR2 (0.66) | PTGDR2HDAC10HDAC6 | |
| SCHEMBL3082812 | 0.77 | PTGDR2 (1.00) | PTGDR2HDAC10HDAC6 | |
| SCHEMBL23148492 | 0.76 | PTGDR2 (0.59) | PTGDR2HDAC10HDAC6 | |
| SCHEMBL5373029 | 0.74 | ENPP2 (0.53) | PTGDR2HDAC10HDAC6ENPP2 | |
| SCHEMBL6421798 | 0.74 | HDAC1 (0.55) | PTGDR2HDAC6ENPP2 | |
| SCHEMBL1120439 | 0.73 | ENPP2 (0.50) | PTGDR2ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169852-A | Anorexigenic agents | NEUREX CORPORATION (US) | 1992-12-08 | — | — | US | disclosed |
| EP-0520987-A4 | METHOD OF SUPPRESSING APPETITE BY ADMINISTRATION OF TETRAHYDRO--g(b)-CARBOLINE DERIVATIVES. | NEUREX CORP (US) | 1992-05-13 | — | — | EP | disclosed |