Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.56 |
| ▸ | HTR5A | P47898 | 2/20 | 0.54 |
| ▸ | HTR6 | P50406 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 4/20 | 0.46 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9615095 | 0.79 | PTGDR2 (0.62) | HDAC6 | |
| SCHEMBL30704369 | 0.78 | HTR5A (0.70) | BCHEHTR5AHDAC1HDAC6GRIN2D | |
| SCHEMBL17486942 | 0.78 | ENPP2 (0.54) | — | |
| SCHEMBL30184445 | 0.78 | CA1 (0.71) | BCHEHTR5AHTR6HDAC1HDAC6 | |
| SCHEMBL1459437 | 0.78 | CA1 (0.71) | BCHEHTR5AHTR6HDAC1HDAC6 | |
| SCHEMBL12938869 | 0.77 | HDAC6 (0.85) | HDAC1HDAC6 | |
| SCHEMBL14157802 | 0.76 | CA1 (0.71) | BCHEHTR5AHTR6HDAC1HDAC6 | |
| SCHEMBL2355269 | 0.76 | MEN1 (0.70) | BCHEHTR5AHDAC1HDAC6MEN1 | |
| SCHEMBL3716587 | 0.76 | MEN1 (0.78) | BCHEHTR5AHDAC1HDAC6GRIN2D | |
| SCHEMBL18494979 | 0.76 | MAOA (0.76) | BCHEHTR5AHTR6HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0535529-B1 | Indole derivatives and anti-ulcer compositions | NISSHIN FLOUR MILLING CO (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5252580-A | Indole derivatives and anti-ulcer compositions thereof | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1993-10-12 | — | — | US | disclosed |
| EP-0535529-A2 | Indole derivatives and anti-ulcer compositions | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1993-04-07 | — | — | EP | disclosed |