Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 2/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.44 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 3/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11246263 | 0.83 | TDO2 (0.33) | EP300KAT2BKAT8CYP3A4HSD17B10 | |
| SCHEMBL28176846 | 0.83 | IDO1 (0.36) | EP300KAT2BKAT8IDO1GAA | |
| SCHEMBL5448026 | 0.76 | GAA (0.38) | GAACYP3A4 | |
| SCHEMBL4808435 | 0.76 | OPRK1 (0.36) | IDO1 | |
| SCHEMBL11470037 | 0.72 | IDO1 (0.47) | EP300KAT8IDO1GAATHRB | |
| SCHEMBL911117 | 0.68 | KDM4E (0.39) | — | |
| SCHEMBL6721139 | 0.67 | IDO1 (0.45) | EP300KAT2BKAT8IDO1HDAC3 | |
| SCHEMBL9615205 | 0.66 | TDO2 (0.33) | HSD17B10 | |
| SCHEMBL3873266 | 0.63 | EP300 (0.39) | EP300KAT2BKAT8IDO1HDAC3 | |
| SCHEMBL5439074 | 0.63 | CYP3A4 (0.39) | GAACYP3A4ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4189433-A | ADRENERGIC BLOCKING AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1980-02-19 | — | — | US | claimed |
| US-6673122-B1 | CONTAINING OXIDIZER | L'ORÉAL (FR) | 2004-01-06 | — | — | US | disclosed |
| US-4189433-A | ADRENERGIC BLOCKING AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1980-02-19 | — | — | US | disclosed |