Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.59 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.59 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10416603 | 0.89 | ZDHHC20 (0.59) | ZDHHC20ZDHHC2DNM1 | |
| Hydrochloric Acid SCHEMBL10416600 | 0.86 | ZDHHC20 (0.59) | ZDHHC20ZDHHC2DNM1 | |
| Hydrochloric Acid SCHEMBL3046560 | 0.83 | ZDHHC20 (0.70) | ZDHHC20ZDHHC2DNM1HSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL11232338 | 0.83 | ZDHHC20 (0.70) | ZDHHC20ZDHHC2DNM1HSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL2489185 | 0.83 | ZDHHC20 (0.70) | ZDHHC20ZDHHC2DNM1HSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL28572838 | 0.83 | ZDHHC20 (0.70) | ZDHHC20ZDHHC2DNM1HSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL31301131 | 0.83 | ZDHHC20 (0.62) | ZDHHC20ZDHHC2DNM1KMT2AATM | |
| Hydrochloric Acid SCHEMBL20528844 | 0.83 | ZDHHC20 (0.62) | ZDHHC20ZDHHC2DNM1KMT2AATM | |
| Hydrochloric Acid SCHEMBL127417 | 0.83 | ZDHHC20 (0.56) | ZDHHC20ZDHHC2KMT2AATM | |
| Hydrochloric Acid SCHEMBL26669425 | 0.83 | ZDHHC20 (0.56) | ZDHHC20ZDHHC2KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104778-A | Layer containing anionic dye, cationic polymer mordant, and gelatin | FUJI PHOTO FILM CO., LTD. (JP) | 1992-04-14 | — | — | US | disclosed |