SCHEMBL961598

SCHEMBL961598

CCCCCCCC[Sn](CCCCCCCC)(CCCCCCCC)c1ccc(C(=O)NN)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.45
MAPT P10636 3/20 0.45
MPO P05164 1/20 0.44
CYP3A4 P08684 1/20 0.44
KDM5A P29375 1/20 0.44
BLM P54132 1/20 0.44
GFER P55789 1/20 0.44
PMP22 Q01453 1/20 0.44
HIF1A Q16665 1/20 0.44
CA2 P00918 2/20 0.44
CA1 P00915 1/20 0.44
ALDH1A1 P00352 3/20 0.43
KDM4E B2RXH2 2/20 0.43
LMNA P02545 2/20 0.43
OGG1 O15527 1/20 0.43
NAAA Q02083 2/20 0.43
HDAC3 O15379 3/20 0.42
HDAC1 Q13547 3/20 0.42
HDAC2 Q92769 3/20 0.42
MLYCD O95822 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL961840 0.94 MAPT (0.47) L3MBTL1MAPTMPOCYP3A4KDM5A
SCHEMBL4769427 0.81 PLK1 (0.58) L3MBTL1CA2CA1HDAC3HDAC1
SCHEMBL4766743 0.79 L3MBTL1 (0.46) L3MBTL1MAPTCA2ALDH1A1LMNA
SCHEMBL4772916 0.78 L3MBTL1 (0.56) L3MBTL1MAPTCA2ALDH1A1NAAA
SCHEMBL8979697 0.77 MAPK1 (0.46) L3MBTL1MAPTCYP3A4BLMPMP22
SCHEMBL6288870 0.76 BDKRB2 (0.44) MAPTALDH1A1LMNA
SCHEMBL8907409 0.76 KDM4E (0.51) L3MBTL1MAPTHIF1ACA2CA1
SCHEMBL9206725 0.76 PLK1 (0.65) MAPTALDH1A1PLK1
SCHEMBL4824490 0.76 PLK1 (0.65) MAPTALDH1A1PLK1
SCHEMBL9164847 0.76 PLK1 (0.65) MAPTALDH1A1PLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2248833-B1 MODIFIED DIENE RUBBER, METHOD FOR PRODUCING THE SAME, RUBBER COMPOSITION USING THE SAME, AND TIRE BRIDGESTONE CORP (JP) 2014-03-26 EP disclosed
US-20130289165-A1 COMPOSITION BASED ON NATURAL RUBBER AND CARBON BLACK COMPRISING A HYDRAZIDE, A HYDRAZONE AND A POLYAMINE MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2013-10-31 US disclosed
US-8389641-B2 Modified diene rubber, production method thereof, and rubber composition and tire using the rubber BRIDGESTONE CORPORATION (JP) 2013-03-05 US disclosed
US-20110003911-A1 MODIFIED DIENE RUBBER, PRODUCTION METHOD THEREOF, AND RUBBER COMPOSITION AND TIRE USING THE RUBBER BRIDGESTONE CORPORATION (JP) 2011-01-06 US disclosed
EP-2248833-A1 MODIFIED DIENE RUBBER, METHOD FOR PRODUCING THE SAME, RUBBER COMPOSITION USING THE SAME, AND TIRE Bridgestone Corporation (JP) 2010-11-10 EP disclosed
US-20100249336-A1 MODIFIED NATURAL RUBBER AND METHOD FOR PRODUCING SAME, AND RUBBER COMPOSITION AND TIRE USING SUCH A MODIFIED NATURAL RUBBER BRIDGESTONE CORPORATION (JP) 2010-09-30 US disclosed
EP-2206730-A1 MODIFIED NATURAL RUBBER, PROCESS FOR PRODUCTION OF THE SAME, AND RUBBER COMPOSITION AND TIRE EACH COMPRISING THE SAME Bridgestone Corporation (JP) 2010-07-14 EP disclosed