Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 9/20 | 0.63 |
| ▸ | P2RY11 | Q96G91 | 3/20 | 0.63 |
| ▸ | ENPP1 | P22413 | 4/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.59 |
| ▸ | SRC | P12931 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.59 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.59 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.59 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | TRPM2 | O94759 | 2/20 | 0.58 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.58 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.58 |
| ▸ | LDHA | P00338 | 1/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1416581 | 0.93 | P2RY1 (0.64) | P2RY1P2RY11ENPP1P2RY2SRC | |
| SCHEMBL5526334 | 0.93 | P2RY1 (0.64) | P2RY1P2RY11ENPP1P2RY2SRC | |
| SCHEMBL19260795 | 0.88 | P2RY1 (0.66) | P2RY1P2RY11ENPP1TSHRKDM4E | |
| Adenosine Diphosphate SCHEMBL29271907 | 0.84 | P2RY1 (0.61) | P2RY1P2RY11ENPP1TSHRKDM4E | |
| SCHEMBL7151766 | 0.84 | P2RY1 (0.64) | P2RY1P2RY11ENPP1P2RY2SRC | |
| Adenosine Triphosphate SCHEMBL27553935 | 0.83 | P2RY1 (0.61) | P2RY1P2RY11ENPP1TSHRKDM4E | |
| Adenosine Phosphate SCHEMBL2063219 | 0.83 | P2RY1 (0.75) | P2RY1P2RY11ENPP1P2RY2SRC | |
| Adenosine Phosphate SCHEMBL28225967 | 0.82 | P2RY1 (0.76) | P2RY1P2RY11ENPP1P2RY2SRC | |
| Adenosine Phosphate SCHEMBL5988433 | 0.82 | P2RY1 (0.76) | P2RY1P2RY11ENPP1P2RY2SRC | |
| Adenosine Diphosphate SCHEMBL584344 | 0.82 | P2RY1 (0.71) | P2RY1P2RY11ENPP1P2RY2SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423290-A4 | METHOD FOR STIMULATING PLANT GROWTH USING SYNTHETICALLY PRODUCED 9-BETA-L(+) ADENOSINE | UNIV MICHIGAN STATE (US) | 1992-10-21 | — | — | EP | disclosed |
| EP-0423290-A1 | METHOD FOR STIMULATING PLANT GROWTH USING SYNTHETICALLY PRODUCED 9-BETA-L(+) ADENOSINE | THE BOARD OF TRUSTEES OF THE MICHIGAN STATE UNIVERSITY (US) | 1991-04-24 | — | — | EP | disclosed |
| US-5009698-A | Method for stimulating plant growth using synthetically produced 9-beta-1(+) adenosine | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) | 1991-04-23 | — | — | US | disclosed |
| WO-1990013223-A1 | METHOD FOR STIMULATING PLANT GROWTH USING SYNTHETICALLY PRODUCED 9-BETA-L(+) ADENOSINE | MICHIGAN STATE UNIVERSITY (US) | 1990-11-15 | — | — | WO | disclosed |