SCHEMBL9617221

SCHEMBL9617221

CCCCCCCCCCCC1=NC(CO)(CO)CO1

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.39
PRKCA P17252 4/20 0.35
SIRT2 Q8IXJ6 1/20 0.32
THRA P10827 1/20 0.32
THRB P10828 1/20 0.32
GAA P10253 2/20 0.32
SCD O00767 1/20 0.32
ALDH1A1 P00352 1/20 0.31
HSD17B10 Q99714 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9404086 1.00 LMNA (0.39) LMNAPRKCASIRT2THRATHRB
SCHEMBL16504781 1.00 LMNA (0.39) LMNAPRKCASIRT2THRATHRB
SCHEMBL11883705 1.00 LMNA (0.39) LMNAPRKCASIRT2THRATHRB
SCHEMBL10957671 0.98 LMNA (0.40) LMNAPRKCAGAAALDH1A1
SCHEMBL6682873 0.93 PRKCA (0.35) LMNAPRKCASIRT2THRATHRB
SCHEMBL10492039 0.93 PRKCA (0.35) LMNAPRKCASIRT2THRATHRB
SCHEMBL10491968 0.93 PRKCA (0.35) LMNAPRKCASIRT2THRATHRB
SCHEMBL676710 0.93 PRKCA (0.35) LMNAPRKCASIRT2THRATHRB
SCHEMBL9414401 0.91 EPHX2 (0.39) PRKCA
SCHEMBL9848776 0.91 EPHX2 (0.39) PRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4224548-A None JP disclosed
US-9109124-B2 Solid ink compositions comprising semicrystalline oligomer resins XEROX CORPORATION (US) 2015-08-18 US disclosed
US-9109124-B2 Solid ink compositions comprising semicrystalline oligomer resins XEROX CORPORATION (US) 2015-08-18 US disclosed
US-8888907-B2 Solid phase change ink compositions comprising oxazolines XEROX CORPORATION (US) 2014-11-18 US disclosed
US-8506694-B2 Phase separation ink XEROX CORPORATION (US) 2013-08-13 US disclosed
US-8500260-B2 Ink compositions incorporating substituted oxazoline compounds or substituted oxazoline derivatives XEROX CORPORATION (US) 2013-08-06 US disclosed
US-8481609-B2 Phase change inks containing oxazoline compounds and polyterpene resins XEROX CORPORATION (US) 2013-07-09 US disclosed
US-8460447-B2 Substituted oxazoline compounds or substituted oxazoline derivatives XEROX CORPORATION (US) 2013-06-11 US disclosed
US-20130032057-A1 SOLID PHASE CHANGE INK COMPOSITIONS COMPRISING OXAZOLINES XEROX CORPORATION (US) 2013-02-07 US disclosed
US-20130035428-A1 Phase Change Inks Containing Oxazoline Compounds and Polyterpene Resins XEROX CORPORATION (US) 2013-02-07 US disclosed
US-20120309896-A1 SOLID INK COMPOSITIONS COMPRISING SEMICRYSTALLINE OLIGOMER RESINS XEROX CORPORATION (US) 2012-12-06 US disclosed
US-20120309896-A1 SOLID INK COMPOSITIONS COMPRISING SEMICRYSTALLINE OLIGOMER RESINS XEROX CORPORATION (US) 2012-12-06 US disclosed
US-20120274710-A1 INK COMPOSITIONS INCORPORATING SUBSTITUTED OXAZOLINE COMPOUNDS OR SUBSTITUTED OXAZOLINE DERIVATIVES XEROX CORPORATION (US) 2012-11-01 US disclosed
US-20120274716-A1 Print Process For Phase Separation Ink XEROX CORPORATION (US) 2012-11-01 US disclosed
US-20120272859-A1 SUBSTITUTED OXAZOLINE COMPOUNDS OR SUBSTITUTED OXAZOLINE DERIVATIVES XEROX CORPORATION (US) 2012-11-01 US disclosed
US-20120274713-A1 Phase Separation Ink XEROX CORPORATION (US) 2012-11-01 US disclosed
JP-H04224548-A PRODUCTION OF FATTY ACID AMIDE KAO CORP 1992-08-13 JP disclosed
EP-0008507-B1 DERIVATIVES OF 2-OXAZOLINES AS ANTIOXIDANTS AND COMPOSITIONS THEREOF UNIROYAL, INC. (US) 1985-02-13 EP disclosed
EP-0008507-A1 Derivatives of 2-oxazolines as antioxidants and compositions thereof UNIROYAL, INC. (US) 1980-03-05 EP disclosed
US-3956305-A Phosphated oxazolines COMMERCIAL SOLVENTS CORPORATION (US) 1976-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120272859-A1 SUBSTITUTED OXAZOLINE COMPOUNDS OR SUBSTITUTED OXAZOLINE DERIVATIVES CDK7, CDK17, ULK2 LMNA 2502/4885PRKCA 2216/4885SIRT2 1325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.