Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SCD | O00767 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10492039 | 1.00 | PRKCA (0.35) | PRKCALMNASIRT2THRATHRB | |
| SCHEMBL10491968 | 1.00 | PRKCA (0.35) | PRKCALMNASIRT2THRATHRB | |
| SCHEMBL6682873 | 1.00 | PRKCA (0.35) | PRKCALMNASIRT2THRATHRB | |
| SCHEMBL9617221 | 0.93 | LMNA (0.39) | PRKCALMNASIRT2THRATHRB | |
| SCHEMBL16504781 | 0.93 | LMNA (0.39) | PRKCALMNASIRT2THRATHRB | |
| SCHEMBL11883705 | 0.93 | LMNA (0.39) | PRKCALMNASIRT2THRATHRB | |
| SCHEMBL9404086 | 0.93 | LMNA (0.39) | PRKCALMNASIRT2THRATHRB | |
| SCHEMBL10957671 | 0.92 | LMNA (0.40) | PRKCALMNAGAA | |
| SCHEMBL322644 | 0.92 | EPHX2 (0.38) | PRKCA | |
| SCHEMBL16666208 | 0.92 | EPHX2 (0.38) | PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 191 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220249446-A1 | Composition Comprising at Least One Oxazoline for Inhibiting the Growth of Malassezia Yeasts Involved in Cradle Cap, in Particular | LABORATOIRES EXPANSCIENCE (FR) | 2022-08-11 | — | — | US | claimed |
| EP-3996674-A1 | COMPOSITION COMPRISING AT LEAST ONE OXAZOLINE FOR INHIBITING THE GROWTH OF MALASSEZIA YEASTS INVOLVED IN CRADLE CAP, IN PARTICULAR | Laboratoires Expanscience (FR) | 2022-05-18 | — | — | EP | claimed |
| EP-2953611-B1 | USE OF A COMPOSITION COMPRISING AVOCADO PERSEOSE IN THE PROTECTION OF EPIDERMAL STEM CELLS | EXPANSCIENCE LAB (FR) | 2021-08-18 | — | — | EP | claimed |
| WO-2021009142-A1 | COMPOSITION COMPRISING AT LEAST ONE OXAZOLINE FOR INHIBITING THE GROWTH OF MALASSEZIA YEASTS INVOLVED IN CRADLE CAP, IN PARTICULAR | LABORATOIRES EXPANSCIENCE (FR) | 2021-01-21 | — | — | WO | claimed |
| US-20200085897-A1 | Extract of Aerial Parts of Maca Rich in Polyphenols and Composition Comprising Same | LABORATOIRES EXPANSCIENCE (FR) | 2020-03-19 | — | — | US | claimed |
| EP-2654765-B1 | EXTRACT OF THE AERIAL PARTS OF MACA RICH IN POLYPHENOL AND COMPOSITION COMPRISING THE EXTRACT | EXPANSCIENCE LAB (FR) | 2019-03-13 | — | — | EP | claimed |
| EP-2654766-B1 | EXTRACT OF THE PULP AND/OR PEEL OF AVOCADO RICH IN POLYPHENOLS AND COSMETIC, DERMATOLOGIC OR NUTRACEUTIC COMPOSITIONS COMPRISING THEREOF | EXPANSCIENCE LAB (FR) | 2018-10-10 | — | — | EP | claimed |
| EP-2654762-B1 | EXTRACT OF THE AERIAL PARTS OF GYNANDROPSIS GYNANDRA AND COSMETIC, DERMATOLIGIC AND PHARMACEUTIC COMPOSITIONS COMPRISING THE EXTRACT | EXPANSCIENCE LAB (FR) | 2018-09-26 | — | — | EP | claimed |
| US-20150374605-A1 | USE OF A COMPOSITION COMPRISING AVOCADO PERSEOSE IN THE PROTECTION OF EPIDERMAL STEM CELLS | LABORATOIRES EXPANSCIENCE (FR) | 2015-12-31 | — | — | US | claimed |
| EP-2953611-A1 | USE OF A COMPOSITION COMPRISING AVOCADO PERSEOSE IN THE PROTECTION OF EPIDERMAL STEM CELLS | Laboratoires Expanscience (FR) | 2015-12-16 | — | — | EP | claimed |
| WO-2006114443-A1 | DEPIGMENTING OR BRIGHTENING COSMETIC COMPOSITION COMPRISING AT LEAST ONE OXAZOLIN AS AN ACTIVE INGREDIENT | LABORATOIRES EXPANSCIENCE (FR) | 2006-11-02 | — | — | WO | claimed |
| US-20060122246-A1 | Cosmetic use of a composition containing at least one oxazoline, serving as an active substance, as a slimming product and/or for preventing and/or treating cellulite | LABORATOIRES EXPANSCIENCE | 2006-06-08 | — | — | US | claimed |
| EP-1648569-A1 | COSMETIC USE OF A COMPOSITION CONTAINING AT LEAST ONE OXAZOLINE, SERVING AS AN ACTIVE SUBSTANCE, AS A SLIMMING PRODUCT AND/OR FOR PREVENTING AND/OR TREATING CELLULITE | Laboratoires Expanscience (FR) | 2006-04-26 | — | — | EP | claimed |
| US-20050075380-A1 | Composition comprising at least one oxazolin for inhibiting langerhans cell migratio, and uses thereof | LABORATOIRES EXPANSCIENCE (FR) | 2005-04-07 | — | — | US | claimed |
| WO-2004112741-A1 | COSMETIC USE OF A COMPOSITION CONTAINING AT LEAST ONE OXAZOLINE, SERVING AS AN ACTIVE SUBSTANCE, AS A SLIMMING PRODUCT AND/OR FOR PREVENTING AND/OR TREATING CELLULITE | LABORATOIRES EXPANSCIENCE (FR) | 2004-12-29 | — | — | WO | claimed |
| EP-1458349-A1 | COMPOSITION COMPRISING AT LEAST AN OXAZOLIN FOR INHIBITING LANGERHANS CELL MIGRATION, AND USES THEREOF | Laboratoires Expanscience (FR) | 2004-09-22 | — | — | EP | claimed |
| WO-2003055463-A1 | COMPOSITION COMPRISING AT LEAST AN OXAZOLIN FOR INHIBITING LANGERHANS CELL MIGRATION, AND USES THEREOF | LABORATOIRES EXPANSCIENCE (FR) | 2003-07-10 | — | — | WO | claimed |
| US-4876249-A | TOPICAL; TRANSDERMAL, SYSTEMIC; FLUOCINOLINE ACETONIDE AND IMIDAZOLINE OR OXAZOLINE PENETRATION ENHANCER MIXTURE; THERAPEUTIC DRUGS | THERAPEUTIC PATCH RESEARCH N.V. | 1989-10-24 | — | — | US | claimed |
| EP-0296199-A1 | HETEROCYCLIC COMPOUNDS FOR TRANSDERMAL USE | RAJADHYAKSHA, Vithal J. (US) | 1988-12-28 | — | — | EP | claimed |
| WO-1988004938-A1 | HETEROCYCLIC COMPOUNDS FOR TRANSDERMAL USE | RAJADHYAKSHA VITHAL J (US) | 1988-07-14 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220249446-A1 | Composition Comprising at Least One Oxazoline for Inhibiting the Growth of Malassezia Yeasts Involved in Cradle Cap, in Particular | OCIAD1, ERG28, CYP51A1 | PRKCA 3638/4885LMNA 4877/4885SIRT2 1681/4885 |
| US-20050075380-A1 | Composition comprising at least one oxazolin for inhibiting langerhans cell migratio, and uses thereof | MIF, CUTA, ARG1 | PRKCA 31/4885LMNA 3183/4885SIRT2 1397/4885 |
| US-20150374605-A1 | USE OF A COMPOSITION COMPRISING AVOCADO PERSEOSE IN THE PROTECTION OF EPIDERMAL STEM CELLS | HES1, PRUNE1, DSG1 | PRKCA 1828/4885LMNA 3069/4885SIRT2 2555/4885 |
| US-20060122246-A1 | Cosmetic use of a composition containing at least one oxazoline, serving as an active substance, as a slimming product and/or for preventing and/or treating cellulite | CUTA, SYMPK, LPXN | PRKCA 2401/4885LMNA 1008/4885SIRT2 1986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.