Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9623900 | 0.83 | HSD17B10 (0.55) | AKR1B1HSD17B10CYP3A4HPGDCRHBP | |
| SCHEMBL9622968 | 0.78 | HSD17B10 (0.48) | HSD17B10CYP3A4HPGDCRHBPCRHR2 | |
| SCHEMBL10491605 | 0.76 | ALDH1A1 (0.54) | AKR1B1HSD17B10CYP3A4HPGDMAPT | |
| SCHEMBL9393694 | 0.74 | CYP1A2 (0.44) | MAPTKDM4EALDH1A1GAAKMT2A | |
| SCHEMBL9617366 | 0.72 | CYP3A4 (0.48) | HSD17B10CYP3A4HPGDCRHBPCRHR2 | |
| SCHEMBL2388019 | 0.71 | CYP3A4 (0.71) | HSD17B10CYP3A4HPGDCRHBPCRHR2 | |
| SCHEMBL9623499 | 0.71 | THRA (0.62) | HSD17B10CYP3A4HPGDCRHBPCRHR2 | |
| SCHEMBL8720641 | 0.69 | TDP1 (0.56) | HSD17B10CYP3A4HPGDCRHBPCRHR2 | |
| SCHEMBL2574718 | 0.68 | HSD17B10 (0.65) | HSD17B10CYP3A4HPGDCRHBPCRHR2 | |
| SCHEMBL70463 | 0.68 | HSD17B10 (0.65) | HSD17B10CYP3A4HPGDCRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4029956-A | — | — | None | — | — | JP | disclosed |
| JP-H0429956-A | 2,6-BIS-(2,6-DICHLORO-4-HYDROXYPHENYLOXY)-1,4-DIHYDROXYBENZENE DERIVATIVE | FUJI KAGAKU KOGYO KK | 1992-01-31 | — | — | JP | disclosed |