Sugi Predict

Sugi Predict / Compounds / Tyrosine

Tyrosine

Tyrosine

SCHEMBL9617523

CC[C@H](C)[C@H](N)C(=O)O.NC(=O)C[C@H](N)C(=O)O.N[C@@H](CS)C(=O)O.N[C@@H](Cc1ccc(O)cc1)C(=O)O.N[C@@H](Cc1ccccc1)C(=O)O.O=C(O)[C@@H]1CCCN1

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SLC5A2

The experimentally established mechanism targets of Tyrosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 2/20 0.39
▸ SLC7A5 Q01650 2/20 0.38
▸ CTSC P53634 1/20 0.37
▸ ACE P12821 4/20 0.36
▸ ALPI P09923 1/20 0.35
▸ PKM P14618 1/20 0.35
▸ PTGS1 P23219 1/20 0.35
▸ XIAP P98170 1/20 0.35
▸ ITGA4 P13612 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dl-Phenylalanine SCHEMBL29176066 0.92 REN (0.44) RENSLC7A5CTSCACEALPI
Tyrosine SCHEMBL10380759 0.90 SLC7A5 (0.41) RENSLC7A5CTSCITGA4
Tyrosine SCHEMBL20855327 0.89 REN (0.35) RENSLC7A5ITGA4
Tyrosine SCHEMBL5151728 0.88 REN (0.36) RENSLC7A5ITGA4
Tyrosine SCHEMBL10379802 0.87 SLC7A5 (0.38) RENSLC7A5CTSCITGA4
Dl-Phenylalanine SCHEMBL29176892 0.84 REN (0.48) RENSLC7A5CTSCACEALPI
Dl-Phenylalanine SCHEMBL28393665 0.84 CTSC (0.44) RENSLC7A5CTSCACEALPI
Phenylalanine SCHEMBL9802538 0.83 REN (0.45) RENSLC7A5CTSCACEALPI
Dl-Phenylalanine SCHEMBL28801804 0.83 ALPI (0.43) RENSLC7A5CTSCALPIPKM
Phenylalanine SCHEMBL3653220 0.83 SLC7A5 (0.51) RENSLC7A5CTSCACEALPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4247100-A — — None — — JP disclosed
JP-H04247100-A NOVEL PEPTIDE, ITS PRODUCTION AND USE THEREOF NIPPON SYNTHETIC CHEM IND CO LTD:THE 1992-09-03 — — JP disclosed